Protein Alignment Nach and Asic3

DIOPT Version :9

• Sequence 1: NP_001334724.1
• Gene: Nach / 36864
• FlyBaseID: FBgn0024319
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: XP_006535700.1
• Gene: Asic3 / 171209
• MGIID: 2159339
• Length: 563
• Species: Mus musculus
• Alignment Length: 557
• Identity: 113/557 - (20%)
• Similarity: 206/557 - (36%)
• Gaps: 140/557 - (25%)

  Fly    24 RRTWSD---FCATSSIHGLKYTRDEDTNKIVHLVW---LLISVVMFICAVVMARTFYMDYRSSPT 82
            ||..||   |..:.::|||.:........:...:|   :|:|:..|:..|.....:|.::....|
Mouse    12 RRQASDIRVFANSCTMHGLGHIFGPGGLTLRRGLWATAVLLSLAAFLYQVAERVRYYGEFHHKTT 76

  Fly    83 RMNVESDNTPVNRLYFPPVTICPDVLFNMQKSEAFLNTLRLPKGAELRGILRKLHIFY------- 140
            ....||     ::|.||.||:|.  :..:::|....|.|.. .|..|.|:....|..|
Mouse    77 LDERES-----HQLTFPAVTLCN--INPLRRSRLTPNDLHW-AGTALLGLDPAEHAAYLRALGQP 133

  Fly   141 ----GFMLDDERYSAEDIEQMEALLFLNNLTIPEFVEHLRWNCDEILYRCRFNGEIMDCS-KIFQ 200
                |||..    ...|:.|:.|              ....:.:::|..||:.|:  .|. :.|.
Mouse   134 PAPPGFMPS----PTFDMAQLYA--------------RAGHSLEDMLLDCRYRGQ--PCGPENFT 178

  Fly   201 LSKTFFGHCCSFNLRQKGWVNNKLNNLESFKVFHLNSLNFTAQRAIGGLRYGLSVVVRYKDDNYD 265
            :..|..|.|.:||...:|                 ..|..|.:   ||...||.:::..:.:.|.
Mouse   179 VIFTRMGQCYTFNSGAQG-----------------AELLTTPK---GGAGNGLEIMLDVQQEEYL 223

  Fly   266 PL------QSYSYGVKLLIQEADAFPSAHSAAKFIAFNSETFAAVRPQE-TF-------CSSAVK 316
            |:      ..:..|:::.|...:..|:........|...:||.:.:.|: :|       |::|
Mouse   224 PIWKDMEETPFEVGIRVQIHGQEEPPAIDQLGFGAAPGHQTFVSCQQQQLSFLPPPWGDCNTA-- 286

  Fly   317 ALIIEERNCVFQNEF------PMRYFSD---YVYPNCELNCRVTNMVKFCGCHTYFFDFNRTSDR 372
                     ....:|      |:...|.   |....|.|.|....:.:.|||.......|   ..
Mouse   287 ---------SVDPDFDPEPSDPLGSPSSSPPYSLIGCRLACESRYVARKCGCRMMHMPGN---SP 339

  Fly   373 ICT---FRDI--PCL---------------VDN--FGRLLLICSKYSDFNRLLSANIITRKKSTQ 415
            :|:   ::|.  |.|               :|:  .|::||       |..|..|:.:.||.:
Mouse   340 VCSPQQYKDCASPALGKAHLFSLPVPIHSDIDHNPLGQVLL-------FLALRPADAMLRKDT-- 395

  Fly   416 CYCPLTCEHIDY--DVQLTNFPLELNMPVADKFYSG----LAKNDGVLHVFINSFSYRRLRRDLL 474
            |.||..|....|  ::.:...|...:.....:.|:.    :.:|..||.:|..:.:|..:.:...
Mouse   396 CVCPNPCATTRYAKELSMVRIPSRASARYLARKYNRSETYITENVLVLDIFFEALNYEAVEQKAA 460

  Fly   475 SNMVTLVSNLGSAFSLFVGMSMLSVVEIIYYFSVILR 511
            ..:..|:.::|....||:|.|:|:::||:.|...:.:
Mouse   461 YEVSELLGDIGGQMGLFIGASLLTILEILDYLCEVFQ 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nach	NP_001334724.1	None
Asic3	XP_006535700.1	ASC	21..546	CDD:383197	109/548 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842194
Domainoid	1	1.000	108	1.000	Domainoid score	I6420
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8693
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4675
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.880