Protein Alignment Nach and Asic1

DIOPT Version :9

• Sequence 1: NP_001334724.1
• Gene: Nach / 36864
• FlyBaseID: FBgn0024319
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_001276720.1
• Gene: Asic1 / 11419
• MGIID: 1194915
• Length: 559
• Species: Mus musculus
• Alignment Length: 557
• Identity: 114/557 - (20%)
• Similarity: 190/557 - (34%)
• Gaps: 157/557 - (28%)

  Fly     4 QEELKPEQVDLKVTPFVGYLRRTWSDFCATSSIHGLKYTRDEDTNKIVHLVW---LLISVVMFIC 65
            :||.|.::..:::..  |...|....|..:.::||..:...|........:|   .:|::..|:|
Mouse    42 EEEEKEKESGMELDE--GDSPRDLVAFANSCTLHGASHVFVEGGPGPRQALWAVAFVIALGAFLC 104

  Fly    66 AVVMARTFYMDYRSSPTRMNVESDNTPVNRLYFPPVTIC------------PDVLF-----NMQK 113
            .|.....:|:.| ...|.:    |......|.||.||.|            ||:|:     .:.:
Mouse   105 QVGDRVAYYLSY-PHVTLL----DEVATTELVFPAVTFCNTNAVRLSQLSYPDLLYLAPMLGLDE 164

  Fly   114 SEAFLNTLRLPKGAELRGILRKLHIFYGFMLDDERYSAEDIEQMEALLFLNNLTIPEFVEHLRWN 178
            |:.....|..|......|....||.||       ..|...:|.|
Mouse   165 SDDPGVPLAPPGPEAFSGEPFNLHRFY-------NRSCHRLEDM--------------------- 201

  Fly   179 CDEILYRCRFNGEIMDCS-KIFQLSKTFFGHCCSFNLRQKGWVNNKLNNLESFKVFHLNSLNFTA 242
               :|| |.:.|.  .|. ..|.:..|.:|.|.:||..|.|     ...|::.|
Mouse   202 ---LLY-CSYCGG--PCGPHNFSVVFTRYGKCYTFNSGQDG-----RPRLKTMK----------- 244

  Fly   243 QRAIGGLRYGLSVVVRYKDDNYDPL------QSYSYGVKLLIQEADAFPSAHSAAKFIAFNSETF 301
                ||...||.:::..:.|.|.|:      .|:..|:|:.|...|..|........:|...:||
Mouse   245 ----GGTGNGLEIMLDIQQDEYLPVWGETDETSFEAGIKVQIHSQDEPPFIDQLGFGVAPGFQTF 305

  Fly   302 AAVRPQETF--------CSSAVKALIIEERNCVFQNEFPMRYFSDYVYPNCELNCRVTNMVKFCG 358
            .:.:.|...        |::.           ...::|    |..|....|.::|....:|:.|.
Mouse   306 VSCQEQRLIYLPSPWGTCNAV-----------TMDSDF----FDSYSITACRIDCETRYLVENCN 355

  Fly   359 CHTYFFDFNRTSDRICTFRDIP-CLVDNFGRLLLICSKYS-DFNRLLSANIITRKKSTQCYCPLT 421
            |......           .|.| |..:.:..    |:..: ||        :..|....|.|.:.
Mouse   356 CRMVHMP-----------GDAPYCTPEQYKE----CADPALDF--------LVEKDQEYCVCEMP 397

  Fly   422 CEHIDYDVQLTNFPLELNMP----------VADKFYSG---LAKNDGVLHVFINSFSYRRLRRDL 473
            |       .||.:..||:|.          :|.||...   :.:|..||.:|....:|..:.:..
Mouse   398 C-------NLTRYGKELSMVKIPSKASAKYLAKKFNKSEQYIGENILVLDIFFEVLNYETIEQKK 455

  Fly   474 LSNMVTLVSNLGSAFSLFVGMSMLSVVEII-YYFSVI 509
            ...:..|:.::|....||:|.|:|:|:|:. |.:.||
Mouse   456 AYEIAGLLGDIGGQMGLFIGASILTVLELFDYAYEVI 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nach	NP_001334724.1	None
Asic1	NP_001276720.1	ASC	63..541	CDD:295594	109/534 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842188
Domainoid	1	1.000	108	1.000	Domainoid score	I6420
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7232
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8693
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.800