Protein Alignment Nach and scnn1d

DIOPT Version :10

• Sequence 1: NP_001334724.1
• Gene: Nach / 36864
• FlyBaseID: FBgn0024319
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: XP_031762206.1
• Gene: scnn1d / 100496702
• XenbaseID: XB-GENE-991876
• Length: 604
• Species: Xenopus tropicalis
• Alignment Length: 574
• Identity: 110/574 - (19%)
• Similarity: 203/574 - (35%)
• Gaps: 174/574 - (30%)

  Fly    30 FCATSSIHGLKYTRDEDTNKIVHLVWLLISVVMFICAVVMARTF------YMDYRSSPTRMNVES 88
            ||..::|||.........||:....||   |:.|:...:|...|      |..|.:: |.:.::|
 Frog    26 FCDNTTIHGTVRLNCSRENKMKTTFWL---VLYFVAFAMMYWQFGQLTDQYWAYPTN-TIIGLQS 86

  Fly    89 DNTPVNRLYFPPVTICPDVLFNMQKSEAFLNTL-RLPKGAELRGILRKLHIFYGFMLDDERYSAE 152
            ...     .||.||||....:...:...::|.| :|.|        ..|::.|.:..:... |.:
 Frog    87 KGK-----IFPAVTICNLNPYRFDQVNMYINQLDQLAK--------ETLYLLYEYEYEVPE-SPQ 137

  Fly   153 DIEQMEALLFLNNLT--------------IPEFVE--------------------------HLRW 177
            .:..::.|  |||:|              :.:..|                          :.:|
 Frog   138 QVVDLQDL--LNNVTGQFNGNFILDQSIVLQKLQENGSGPALPGQKKFKVGFKLCNSSGDCYYKW 200

  Fly   178 ---------------------NCDEIL-----------YRCRFNGEIMDCSKIFQLSKTFFGHCC 210
                                 |...:|           ..|.||....|..:........:|:|.
 Frog   201 FWSGFDAVHEWYKFHYINIMSNIPAVLNIANNFSRDYILTCHFNEMPCDEREYVHFHHPIYGNCF 265

  Fly   211 SFN--LRQKGWVNNKLNNLESFKVFHLNSLNFTAQRAIGGLRYGLSVVVRYKDDNYD--PLQSYS 271
            :.|  .::..|.:::                       .|.:||||:||  |.|.:|  ||.|.:
 Frog   266 TINNHWKENSWYSSR-----------------------PGKQYGLSIVV--KTDLHDNMPLLSQA 305

  Fly   272 YGVKLLIQEADAFPSAHSAAKFIAFNSETFAAVRPQETF--------CSSAVKALIIEERNCVFQ 328
            .|.:::|...:..|........|...:|...:|:.:|..        |:|....|.|:
 Frog   306 AGARIMIHNPNQPPLVEHQGFDIRPGTENSISVKQEEAIRLGGKYSQCTSDGSDLGIK------- 363

  Fly   329 NEFPMRYFSDYVYPNCELNCRVTNMVKFCGCHTYFFDFNRTSDRICTFRDIPCLVDNFGRLLLIC 393
                :.|.:.|....|..:|....|::.|||..||:......: .|.:...|    ::|...
 Frog   364 ----ILYNTSYTMQACLNSCFQYKMIEVCGCGYYFYPLPPGME-YCNYNKHP----DWGYCF--- 416

  Fly   394 SKYSDFNRLLSANIITRKKSTQCY--CPLTCEHIDYDVQ--LTNFPLELN-----MPVADKFYSG 449
              |..:.::|...:|       |:  ||..|:..:|.:.  ...:|..::     :.:.:::.|.
 Frog   417 --YQLYEKMLDHTLI-------CFTQCPKQCKQTEYHLSAGTAKWPSPVSKAKKLLSLQERYNST 472

  Fly   450 LAKND-GVLHVFINSFSYRRLRRDLLSNMVTLVSNLGSAFSLFVGMSMLSVVEI 502
            ..::| ..::|:....|||.:......::..|:|::|..:|.:.|.|:|||.||
 Frog   473 SKRSDISKINVYYEELSYRSVEETPSVSVTMLLSSMGGLWSWWFGSSVLSVAEI 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nach	NP_001334724.1	ASC	30..505	CDD:459966	110/574 (19%)
scnn1d	XP_031762206.1	ENaC	18..583	CDD:273304	110/574 (19%)