DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Amyrel and MAL32

DIOPT Version :9

Sequence 1:	NP_477262.1	Gene:	Amyrel / 36863	FlyBaseID:	FBgn0020506	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_009858.3	Gene:	MAL32 / 852602	SGDID:	S000000503	Length:	584	Species:	Saccharomyces cerevisiae

Alignment Length:	408	Identity:	86/408 - (21%)
Similarity:	147/408 - (36%)	Gaps:	134/408 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LSLAQH---NPHWWGNRNTIVHLF--EWK------WSD---IAQECESFLGPRGFAGVQVSPVNE 66
            ::::.|   .|.|| ...||..::  .:|      |.|   |..:.: ::...|...:.|.|..:
Yeast     1 MTISDHPETEPKWW-KEATIYQIYPASFKDSNNDGWGDLKGITSKLQ-YIKDLGVDAIWVCPFYD 63

  Fly    67 NILSAGRPWWERYQPIS--YKLTTRSGNEEEFGDMVRRCNDVGVRIYVDVLLNHMSGDFDGVAVG 129
            :      |..:....||  .|:....|..|:..:::.:.:.:|::...|:::||.|.:.:.....
Yeast    64 S------PQQDMGYDISNYEKVWPTYGTNEDCFELIDKTHKLGMKFITDLVINHCSTEHEWFKES 122

  Fly   130 TA----------------GTEAE-----PSK-KSFPG-----VPYTAQDFHPTCEITDWNDRFQV 167
            .:                |.:||     |:. |||.|     ...|..:|:...        |..
Yeast   123 RSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSFFGGSAWTFDETTNEFYLRL--------FAS 179

  Fly   168 QQCELVGLKDLDQSSDWVRSKLIE-----FLDHLIELGVAGFRVDAA----KHMASEDLEYIYSS 223
            :|.      ||:..::..|..:.|     :|||    ||.|||:|.|    |.....| ..|:..
Yeast   180 RQV------DLNWENEDCRRAIFESAVGFWLDH----GVDGFRIDTAGLYSKRPGLPD-SPIFDK 233

  Fly   224 LSNLNIDHGFPHNS----------RPFIFQEVID-----------HG-----HETVSRDEYKDLG 262
            .|.|...:...||.          ..|:...|.|           ||     :.:.:|.|..::
Yeast   234 TSKLQHPNWGSHNGPRIHEYHQELHRFMKNRVKDGREIMTVGEVAHGSDNALYTSAARYEVSEV- 297

  Fly   263 AVTEFRFSE-EIGNA--FRGNNALKWLQSW------------GTD-WGFLPSGQALTFVDNHDNQ 311
                |.|:. |:|.:  ||.|.....|:.|            ||| |       |.|:::|||..
Yeast   298 ----FSFTHVELGTSPFFRYNIVPFTLKQWKEAIASNFLFINGTDSW-------ATTYIENHDQA 351

  Fly   312 RDAGAVLNYKSPRQYKMA 329
            |......: .||:..|::
Yeast   352 RSITRFAD-DSPKYRKIS 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Amyrel	NP_477262.1	AmyAc_bac_euk_AmyA	29..398	CDD:200456	82/392 (21%)
Amyrel	NP_477262.1	Aamy_C	404..492	CDD:214749
MAL32	NP_009858.3	AmyAc_SI_OligoGlu_DGase	15..501	CDD:200472	82/393 (21%)
MAL32	NP_009858.3	Malt_amylase_C	511..583	CDD:406946
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342143
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0366
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830