DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Amyrel and Mal-A4

DIOPT Version :9

Sequence 1:	NP_477262.1	Gene:	Amyrel / 36863	FlyBaseID:	FBgn0020506	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_610381.1	Gene:	Mal-A4 / 35827	FlyBaseID:	FBgn0033294	Length:	579	Species:	Drosophila melanogaster

Alignment Length:	369	Identity:	79/369 - (21%)
Similarity:	127/369 - (34%)	Gaps:	147/369 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 LSAGRPWWER---YQ--PISYK------------LTTR--------------------------- 89
            :.|..|||:.   ||  |.|:|            :|.:
  Fly    18 VDAAAPWWKTASFYQIYPRSFKDSDGNGVGDLNGVTEKLEYLKEIGVTATWLSPFLKSPMADFGY 82

  Fly    90 -----------SGNEEEFGDMVRRCNDVGVRIYVDVLLNHMSGDFDGVAVGTAGTEAEPSKKSF- 142
                       .|..|:|.:||.|..::||:|.:|.:.||.|.:.|......||   |...|.:
  Fly    83 DISDFKAVDPLFGTMEDFENMVSRAKELGVKIILDFVPNHSSDECDWFLRSAAG---EEEYKDYY 144

  Fly   143 ---PGVPYTAQD---FHPTCEIT-------DWND--------RFQVQQCELVGLKDLDQSSDWVR 186
               ||  :..:|   ..||..::       :|::        :|..:|      .|.:..:..||
  Fly   145 MWHPG--FLDEDGTRRPPTNWVSVFRGSAWEWHEGRQEYYLHQFHKKQ------PDFNFRNPVVR 201

  Fly   187 SKLIEFLDHLIELGVAGFRVDAAKHM----ASEDLEY---IYSSLSNLNIDHGFPHN-------S 237
            .::...|...:|.||.||||||..|.    |.|:..|   ..:..:|...::|:.|.       .
  Fly   202 EEMNNVLRFWLEKGVDGFRVDAIYHAFEIEADENGNYPDEPRNDWTNDPDEYGYTHKIYTVDQPE 266

  Fly   238 RPFI----------FQ------------------EVIDH--GHETVSRDEYKDLGAVTEFRFSEE 272
            .|.:          ||                  |::.|  |:||..       ||...|.| :.
  Fly   267 TPHLVYEWRQILEQFQADNGGDERILMVETWSPIEIVMHYYGNETAD-------GAQIPFNF-QL 323

  Fly   273 IGNAFRGNNALKW---LQSWGTDWGFLPSGQALTFV-DNHDNQR 312
            |.|....::|..:   :.:|   ...:|.|::..:| .|||..|
  Fly   324 ISNLHYDSDAYHYEYLINNW---LNLMPEGKSANWVIGNHDKNR 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Amyrel	NP_477262.1	AmyAc_bac_euk_AmyA	29..398	CDD:200456	79/369 (21%)
Amyrel	NP_477262.1	Aamy_C	404..492	CDD:214749
Mal-A4	NP_610381.1	AmyAc_maltase	24..492	CDD:200467	77/363 (21%)
Mal-A4	NP_610381.1	Alpha-amylase	47..401	CDD:278554	70/340 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45443615
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0366
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830