DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Amyrel and mal1

DIOPT Version :9

Sequence 1:	NP_477262.1	Gene:	Amyrel / 36863	FlyBaseID:	FBgn0020506	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_595063.1	Gene:	mal1 / 2539976	PomBaseID:	SPBC1683.07	Length:	579	Species:	Schizosaccharomyces pombe

Alignment Length:	413	Identity:	81/413 - (19%)
Similarity:	151/413 - (36%)	Gaps:	109/413 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 PHWWGNRNTIVH-LFEWKWSDIAQECESFLGPRGFAGVQ--VSPVNE-NILSAGRPWW------- 76
            |:||  |.|.|: ::...:.|...:        ||..::  :|.|:. ..|:....|.
pombe    11 PNWW--RETSVYQIYPASFKDSNGD--------GFGDLEGIISKVDYLKALNVESIWLCPIYPSP 65

  Fly    77 ---ERYQPISYK-LTTRSGNEEEFGDMVRRCNDVGVRIYVDVLLNHMSGDFDGVAVGTAGTEAEP 137
               ..|....|| :.:|.|..|:...:::..::..:::.:|::|||.|...:... .:..::..|
pombe    66 LKDMGYDVSDYKQIDSRYGTLEDLDRLMKALHERDMKLVMDLVLNHTSDQHEWFK-ESRSSKTNP 129

  Fly   138 SKKSFPGVPYTAQDFHPTCEITDWNDRFQVQQCE-------------LVGLKDLDQSSDWVRSKL 189
            .:..:...|....:........:|...|.....|             .||..||:..:..||..:
pombe   130 KRDWYFWKPARYNEKGERLPPNNWRSYFDTSAWEWDEATQEYYLHLWSVGQPDLNWETPKVREAV 194

  Fly   190 IEFLDHLIELGVAGFRVDAAKHMASED----------------LEYIY-----------SSLSNL 227
            .:.|...::.||.|||:||. :|.|:|                |.|.|           :.:.|:
pombe   195 HDILRFWLDRGVDGFRLDAI-NMISKDQRFLDAPITDDRYEYQLAYQYYANGPRIHEYLNGIGNI 258

  Fly   228 NIDH-GFPHNSRPFIF--QEVIDHGHETVSRDEYKDLGAVTEFRF---------SEEIGNAFRGN 280
            ..:: .|.....|::.  .|::    ..|..|. ::|..:.:|.|         .:.|..::..:
pombe   259 LTEYDAFSVGEMPYVLDTNEIL----HVVGADR-RELTMIFQFDFVDLDLDPNQHKYIEGSWELS 318

  Fly   281 NALKWLQSW------GTDWGFLPSGQALTFVDNHDNQRDAGAVLNYKSPRQYKMATAFHLAYPYG 339
            :..|.|:.|      |..|.       .:|::|||..|.....|: .||:        :.||.
pombe   319 DLKKSLKKWQSALLSGGGWN-------ASFIENHDQTRTVSRYLS-DSPK--------YRAYS-- 365

  Fly   340 ISRVMSSFAFDDHDTPPPQDAQE 362
             |::|:.|......||.....||
pombe   366 -SKLMALFIIFQSGTPFVFQGQE 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Amyrel	NP_477262.1	AmyAc_bac_euk_AmyA	29..398	CDD:200456	78/407 (19%)
Amyrel	NP_477262.1	Aamy_C	404..492	CDD:214749
mal1	NP_595063.1	trehalose_treC	13..579	CDD:274115	80/411 (19%)
		AmyAc_SI_OligoGlu_DGase	15..496	CDD:200472	78/407 (19%)
		Malt_amylase_C	504..576	CDD:295440
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0366
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900