DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Amyrel and SPCC757.12

DIOPT Version :9

Sequence 1:	NP_477262.1	Gene:	Amyrel / 36863	FlyBaseID:	FBgn0020506	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_587687.1	Gene:	SPCC757.12 / 2538825	PomBaseID:	SPCC757.12	Length:	625	Species:	Schizosaccharomyces pombe

Alignment Length:	549	Identity:	119/549 - (21%)
Similarity:	201/549 - (36%)	Gaps:	141/549 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KFALTLTLCLAG-SLSLAQHNPHWWGNRNTIVH-----------------LFE------WKWSDI 43
            |.||.....|.| ..|||:.:..|   |:.|::                 .|:      ..||.|
pombe     5 KIALFSLFALFGLPTSLAKSSEEW---RDRIIYQVITDRFAVDSDNTPDCSFDDSSYCGGTWSGI 66

  Fly    44 AQECESFLGPRGFAGVQVSPVNENIL----SAGRPWWERYQPISYKLTTRSGNEEEFGDMVRRCN 104
            ..:.:...| .||..:.:|||.:|:.    |.|..:...:.....:|....|:|::..|::...:
pombe    67 RSKLDYIQG-MGFNAIWISPVEKNLEGSYGSDGEAYHGYWNTDFTQLNEHFGSEDDLIDLITDMH 130

  Fly   105 DVGVRIYVDVLLNHMS--GDFDGVAVGTAGTEAEPSKKSFPGVPYT-AQDFHPTCEITDW--NDR 164
            :..:.|..|.|.|.|:  |..|.::....             ||:. :..|||.|.| |:  |:.
pombe   131 NRDMWIMFDALANSMAIPGPTDNISYSNL-------------VPFNDSSYFHPYCWI-DYGSNNN 181

  Fly   165 FQVQQC----ELVGLKDLDQSSDWVRSKLIEFLDHLIE-LGVAGFRVDAAKHMASEDLEYIYSSL 224
            ..::.|    :.|.|.|||..|..|...|.|.:..::| ..:.|.|:||.|.|..|.... |:|.
pombe   182 TDIEDCWTGDDNVILADLDIESTNVADYLHEHIHDMVERYQIDGIRIDAVKQMNPEFFPN-YTSA 245

  Fly   225 SNLNIDHGFPHNSRPFIFQEVIDHGHETVSRDEYKDLGAVTEFRFSEEIGNAFRGNN-ALKWLQS 288
            :.:            |...|:..: ...||......|.::|.:...:.|..||.... |.::||.
pombe   246 AGV------------FAIGEMFSY-DPNVSCSVRNYLDSITSYPIRQGIEFAFNYTGAAFEYLQE 297

  Fly   289 WGTDWGFLPSGQALT----FVDNH----------DNQRDAGAVLNYKSPRQYKMATAFHLAYP-- 337
            ..|.:.....||.::    |::||          |..:|.||:          :....|...|
pombe   298 IDTQFQQACEGQDMSVIGNFLENHDLPRYTSITNDTSQDIGAI----------VFLLLHTGIPII 352

  Fly   338 -YGISRVMSSFAFDDHDTPPPQDAQERIISPEFDADGACVNGWICEHRWRQIYAMVGF-KNAVRD 400
             ||..:.:..    ..|||..:.|   :.:..:|.|.         :.::.|...:.. |.|:.|
pombe   353 YYGEEQRLPG----GSDTPENRAA---LWNYGYDTDA---------NYYQTIRTAIALRKQAISD 401

  Fly   401 TEITGWWDNG----DNQISFCRGNKG-FLAINNNLYDLSQDLNTCLPAGTYCDVISGSLIDGSCT 460
            ::  .|..:.    |..:......|| .|.:..| |:.|.|..|...:..:.|   |:::....:
pombe   402 SD--SWTTDSHSYLDYDLRHAVVRKGDVLGVYTN-YESSSDNVTYDVSSNFDD---GTVLREVLS 460

  Fly   461 GKSVTVNENGYGYIHIGSDDFDGVLALHV 489
            ..:.||..:|               ||||
pombe   461 NTTTTVGSSG---------------ALHV 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Amyrel	NP_477262.1	AmyAc_bac_euk_AmyA	29..398	CDD:200456	89/424 (21%)
Amyrel	NP_477262.1	Aamy_C	404..492	CDD:214749	19/91 (21%)
SPCC757.12	NP_587687.1	AmyAc_euk_AmyA	23..401	CDD:200458	91/435 (21%)
		Alpha-amylase	61..365	CDD:278554	78/346 (23%)
		DUF1966	422..490	CDD:286359	17/72 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0366
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X338
TreeFam	0	0.000	Not matched by this tool.
	3	2.810