Protein Alignment Amyrel and Amy2a3

DIOPT Version :10

• Sequence 1: NP_477262.1
• Gene: Amyrel / 36863
• FlyBaseID: FBgn0020506
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_001153623.1
• Gene: Amy2a3 / 100043686
• MGIID: 3714985
• Length: 508
• Species: Mus musculus
• Alignment Length: 515
• Identity: 253/515 - (49%)
• Similarity: 332/515 - (64%)
• Gaps: 32/515 - (6%)

  Fly     3 KFALTLTLCLAGSLSLAQHNPHWWGNRNTIVHLFEWKWSDIAQECESFLGPRGFAGVQVSPVNEN 67
            ||.|.|:|.   ....||::||....|..|||||||:|.|||:|||.:|.|:||.||||||.|||
Mouse     2 KFVLLLSLI---GFCWAQYDPHTSDGRTAIVHLFEWRWVDIAKECERYLAPKGFGGVQVSPPNEN 63

  Fly    68 IL--SAGRPWWERYQPISYKLTTRSGNEEEFGDMVRRCNDVGVRIYVDVLLNHMSGDFDGVAVGT 130
            ::  :..|||||||||||||:.||||||:||.|||.|||:||||||||.::|||.|  .|...||
Mouse    64 VVVHNPSRPWWERYQPISYKICTRSGNEDEFRDMVTRCNNVGVRIYVDAVINHMCG--AGNPAGT 126

  Fly   131 A---GTEAEPSKKSFPGVPYTAQDFHPT-C--EITDWNDRFQVQQCELVGLKDLDQSSDWVRSKL 189
            :   |:...|:.:.||.|||:|.||:.. |  ||.::||.:||:.|.|.||.||....|:||:|:
Mouse   127 SSTCGSYLNPNNREFPAVPYSAWDFNDNKCNGEIDNYNDAYQVRNCRLTGLLDLALEKDYVRTKV 191

  Fly   190 IEFLDHLIELGVAGFRVDAAKHMASEDLEYIYSSLSNLNIDHGFPHNSRPFIFQEVIDHGHETVS 254
            .::::|||::||||||:||||||...|::.:...|.||| ...|...|||||||||||.|.|.:.
Mouse   192 ADYMNHLIDIGVAGFRLDAAKHMWPGDIKAVLDKLHNLN-TKWFSQGSRPFIFQEVIDLGGEAIK 255

  Fly   255 RDEYKDLGAVTEFRFSEEIGNAFRGNNA--LKWLQSWGTDWGFLPSGQALTFVDNHDNQRDAGA- 316
            ..||...|.||||::..::|...|..|.  :.:|::||..||.:||.:||.|||||||||..||
Mouse   256 GSEYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGLVPSDRALVFVDNHDNQRGHGAG 320

  Fly   317 ---VLNYKSPRQYKMATAFHLAYPYGISRVMSSFAF--------DDHD--TPPPQDAQERIISPE 368
               :|.:...|.||||..|.||:|||.:|||||:.:        |.:|  .||..:...:.::
Mouse   321 GSSILTFWDARMYKMAVGFMLAHPYGFTRVMSSYRWNRNFQNGKDQNDWIGPPNNNGVTKEVT-- 383

  Fly   369 FDADGACVNGWICEHRWRQIYAMVGFKNAVRDTEITGWWDNGDNQISFCRGNKGFLAINNNLYDL 433
            .:||..|.|.|:||||||||..||.|:|.|.....:.||||..||::|.|||:||:..||:.:.|
Mouse   384 INADTTCGNDWVCEHRWRQIRNMVAFRNVVNGQPFSNWWDNNSNQVAFSRGNRGFIVFNNDDWAL 448

  Fly   434 SQDLNTCLPAGTYCDVISGSLIDGSCTGKSVTVNENGYGYIHIGSDDFDGVLALHVDAKV 493
            |..|.|.||||||||||||..:||:|||..|.|..:|..:..|.:...|..:|:|.|:|:
Mouse   449 SATLQTGLPAGTYCDVISGDKVDGNCTGLRVNVGSDGKAHFSISNSAEDPFIAIHADSKL 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Amyrel	NP_477262.1	AmyAc_bac_euk_AmyA	29..398	CDD:200456	199/392 (51%)
		Aamy_C	404..492	CDD:214749	43/87 (49%)
Amy2a3	NP_001153623.1	AmyAc_bac_euk_AmyA	25..413	CDD:200456	199/392 (51%)
		Aamy_C	420..507	CDD:214749	43/86 (50%)