DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Amyrel and si:dkey-202g17.3

DIOPT Version :9

Sequence 1:	NP_477262.1	Gene:	Amyrel / 36863	FlyBaseID:	FBgn0020506	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	XP_001343266.1	Gene:	si:dkey-202g17.3 / 100003805	ZFINID:	ZDB-GENE-131127-371	Length:	487	Species:	Danio rerio

Alignment Length:	426	Identity:	79/426 - (18%)
Similarity:	122/426 - (28%)	Gaps:	171/426 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KFALTLTLC--------LAGSLSLAQHNP-------HWWGNRNTIVHLFEWKWSDIAQECESFLG 52
            ||...|.||        |..::.:...:|       ||| .|:.|..|....:.|..::.:|
Zfish    65 KFRRRLVLCFWICWMLLLGAAVLIVIRSPRATSPVLHWW-QRDLIYRLQPMLFLDADRQQDS--- 125

  Fly    53 PRGFAGVQVSPVNENI-----LSAGRPWWERYQPISYKLTTRSGNEEEFG------DMVRRCNDV 106
                   :::.|.|.:     :.||....|.....|...|..:..::..|      .::......
Zfish   126 -------RINRVCERLPYLKSVGAGAVILEGLFGNSSSSTNLTEIDQNLGTLPQLTQLITESRKA 183

  Fly   107 GVRIYVDVL------------------------------LNHMSGDFDGVAVGTAGTEAEPSKKS 141
            |||:.:|:.                              |:|....|     |...|:|..|.|:
Zfish   184 GVRVILDLCELDLFEQESNNDTAVWSGASESIQYSLRYWLDHGVSGF-----GICDTDAAFSAKT 243

  Fly   142 FPGVPYTAQDFHPTCEITDWN---DRFQVQQCELV--------GLKDLDQSSDWVRSKLIEFLDH 195
                            :.:||   ..|..|..|.:        .|..|:.||         |...
Zfish   244 ----------------LMEWNKLMQEFSSQDDERILMVRQTGNTLPVLNVSS---------FAGS 283

  Fly   196 LIELGVAGFRVDAAKHMAS--EDLEYIYSSLS-------NLNIDHGFPHNSRPFIF--------Q 243
            |:|| |....:..:.|..|  |..|.|..||.       :..:..|.|......|.        .
Zfish   284 LVEL-VTKSLIPPSHHPLSTAEVAEAIEVSLQMPQRDWPSWTVGGGVPRELNRAILLLIMTLPGT 347

  Fly   244 EVIDHGHETVS----------------------RDEYKDLGAVTEFRFSEEIGNAFRGNNA---- 282
            .:|.:|.|..|                      |:|....|..|...|:..:.::...|..
Zfish   348 PIIKYGDELSSAQGWNRLNQPLALFQSLSQSRAREEALHFGRFTFLSFNTSLPSSSGLNTTDTPL 412

  Fly   283 LKWLQSWG------------------TDWG-FLPSG 299
            |.:|:|||                  .||. .||.|
Zfish   413 LAYLRSWGCVHFLVLFNLGSAPHTMDPDWAPSLPEG 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Amyrel	NP_477262.1	AmyAc_bac_euk_AmyA	29..398	CDD:200456	69/385 (18%)
Amyrel	NP_477262.1	Aamy_C	404..492	CDD:214749
si:dkey-202g17.3	XP_001343266.1	SLC3A2_N	49..105	CDD:292647	10/40 (25%)
		AmyAc_family	93..404	CDD:298606	62/352 (18%)
		Alpha-amylase	132..362	CDD:278554	47/260 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576488
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0366
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.830