Protein Alignment gprs and spop

DIOPT Version :10

• Sequence 1: NP_725599.2
• Gene: gprs / 36862
• FlyBaseID: FBgn0024232
• Length: 1302
• Species: Drosophila melanogaster
• Sequence 2: NP_989003.1
• Gene: spop / 394599
• XenbaseID: XB-GENE-1003310
• Length: 374
• Species: Xenopus tropicalis
• Alignment Length: 247
• Identity: 49/247 - (19%)
• Similarity: 99/247 - (40%)
• Gaps: 69/247 - (27%)

  Fly    15 PDLSTFENKTGLAEDMKFLASMPELCDVTFLVGDTREPVCAVKAVLASRSRVFAKMLYAAPSPQR 79
            |:....:...||.|:.:|....  ||    :.|...:   |.||:||:||.||:.|.      :.
 Frog   182 PECRLADELGGLWENSRFTDCC--LC----VAGQEFQ---AHKAILAARSPVFSAMF------EH 231

  Fly    80 KRETSTKENKLRLFLKRSSEPLLNLQNAAQQRTGYTQQLAPIPEPSGQQHQTLIIEEFEPDVFRQ 144
            :.|.| |:|::.                                          |::.|||||::
 Frog   232 EMEES-KKNRVE------------------------------------------IKDVEPDVFKE 253

  Fly   145 LIEYIHTGCVTLQPRTLLGVMNAADYYGLEELRRACAGFVQCCINVDTVCALLASAERYIQYKCT 209
            ::.:|:||..:...:....::.|||.|.||.|:..|...:...::|:....:|..|:.:    ..
 Frog   254 MMCFIYTGKASNLDKMADDLLAAADKYALERLKVMCEEALCSNLSVENAAEILILADLH----SA 314

  Fly   210 KTLVQKVLEFVDEHGTEVLNLGSFTLLPQHVVRLILAREELRADEFTKFQAA 261
            ..|..:.::|::.|.::|:....:.       .::::...|.|:.:....:|
 Frog   315 DQLKTQAVDFINYHASDVMETSGWK-------SMVVSHPHLVAEAYRSLASA 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gprs	NP_725599.2	BTB_POZ_BTBD19	26..184	CDD:349603	37/157 (24%)
		BACK_GPRS_like	189..268	CDD:350582	10/73 (14%)
spop	NP_989003.1	MATH_SPOP	28..166	CDD:239743
		Required for nuclear localization. /evidence=ECO:0000250	71..191		1/8 (13%)
		BTB_POZ_SPOP-like	182..301	CDD:349588	40/176 (23%)
		BACK_SPOP	297..367	CDD:350593	10/74 (14%)
		Homodimerization. /evidence=ECO:0000250	297..355		9/68 (13%)