Protein Alignment gprs and Klhl41

DIOPT Version :10

• Sequence 1: NP_725599.2
• Gene: gprs / 36862
• FlyBaseID: FBgn0024232
• Length: 1302
• Species: Drosophila melanogaster
• Sequence 2: NP_476539.1
• Gene: Klhl41 / 117537
• RGDID: 620852
• Length: 606
• Species: Rattus norvegicus
• Alignment Length: 250
• Identity: 38/250 - (15%)
• Similarity: 87/250 - (34%)
• Gaps: 58/250 - (23%)

  Fly    24 TGLAEDMKFLASMPELCDVTFLVGDTREPVCAVKAVLASRSRVFAKMLYAAPSPQRKRETSTKEN 88
            |.|.:.:|.|....:..|.|...||...| |. :.:|::.|..|.:...:....::|:|
  Rat    17 TLLQDGLKDLLEEKKFIDCTLKAGDKSFP-CH-RLILSACSPYFREYFLSEIEEEKKKE------ 73

  Fly    89 KLRLFLKRSSEPLLNLQNAAQQRTGYTQQLAPIPEPSGQQHQTLIIEEFEPDVFRQLIEYIHTGC 153
                                                       :.::..:|.:...:|:|:::..
  Rat    74 -------------------------------------------MALDNVDPAILDLIIKYLYSAS 95

  Fly   154 VTLQPRTLLGVMNAADYYGLEELRRACAGFVQCCINVDTVCALLASAERYIQYKCTKTLVQKVLE 218
            :.|....:..:...:..:.:..:...|..::|..:......|:|...   :...|.: |.....|
  Rat    96 IDLNDGNVQDIFALSSRFQIPSVFTVCVSYLQKRLAPGNCLAILRLG---LLLDCPR-LAISARE 156

  Fly   219 FVDEHGTEVLNLGSF-TLLPQHVVRLILAREELRAD-EFTKFQAALMWSKKYYDN 271
            ||.:...::.....| .|.||.::. :::.:.|..: |...|:|.:.|.:...:|
  Rat   157 FVSDRFVQICKEEDFMQLSPQELIS-VISNDSLNVEKEEVVFEAVMKWVRTDKEN 210

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gprs	NP_725599.2	BTB_POZ_BTBD19	26..184	CDD:349603	19/157 (12%)
		BACK_GPRS_like	189..268	CDD:350582	16/80 (20%)
Klhl41	NP_476539.1	BTB_POZ_KLHL41_KBTBD10	6..135	CDD:349650	21/168 (13%)
		PHA03098	39..578	CDD:222983	31/227 (14%)
		KELCH repeat	335..384	CDD:276965
		Kelch 1	346..398
		KELCH repeat	388..433	CDD:276965
		Kelch 2	399..447
		KELCH repeat	437..482	CDD:276965
		Kelch 3	448..495
		KELCH repeat	485..530	CDD:276965
		Kelch 4	497..542
		Kelch 5	544..599