DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5065 and LYS2

DIOPT Version :9

Sequence 1:	NP_001163168.1	Gene:	CG5065 / 36860	FlyBaseID:	FBgn0034145	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_009673.1	Gene:	LYS2 / 852412	SGDID:	S000000319	Length:	1392	Species:	Saccharomyces cerevisiae

Alignment Length:	313	Identity:	76/313 - (24%)
Similarity:	130/313 - (41%)	Gaps:	65/313 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 SVFITGGTGFMGKVLVEKLLRSCPEIRN--IYLLIRPKRGQEVSARLTELLNAPLFESLRQEKPK 189
            :||:||.|||:|..::..||...|:..:  ::..:|.|..:...|||.:   |.:......||..
Yeast   972 NVFVTGVTGFLGSYILADLLGRSPKNYSFKVFAHVRAKDEEAAFARLQK---AGITYGTWNEKFA 1033

  Fly   190 ELSKVIPISGDITSEELGISEKDQNLLCRNVSVVFHSAATVKF---DEKLK---LSVTINML--- 245
            ...||  :.||::..:.|:|::....|...|.::.|:.|.|.:   ..||:   :..|||::
Yeast  1034 SNIKV--VLGDLSKSQFGLSDEKWMDLANTVDIIIHNGALVHWVYPYAKLRDPNVISTINVMSLA 1096

  Fly   246 --GTKRLVELCHRMLSLDALIHVSTAYCNCDRTDVSEVIYAPP--YNPDDIISLINWLPEDILDQ 306
              |..:..:......:||     :..|.|.....|||   ..|  ...||:::..:.|
Yeast  1097 AVGKPKFFDFVSSTSTLD-----TEYYFNLSDKLVSE---GKPGILESDDLMNSASGL------- 1146

  Fly   307 LTPRLIGKRPNTYTFTKALAEHMLLKEAG--NLPVAIVRPSIVTASLNEPFAGWVDNFNGPTGLV 369
                     ...|..:|..||: :::.||  .|...||||..||.:          :.||.:...
Yeast  1147 ---------TGGYGQSKWAAEY-IIRRAGERGLRGCIVRPGYVTGA----------SANGSSNTD 1191

  Fly   370 SALAKGMFRTMMCEK-----NYVADMVPVDIVINLMIAAAWRTATRKSNNLLI 417
            ..|.:.:..::...|     |.| :|||||.|..:::|.:....  |.|.|.:
Yeast  1192 DFLLRFLKGSVQLGKIPDIENSV-NMVPVDHVARVVVATSLNPP--KENELAV 1241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5065	NP_001163168.1	FAR-N_SDR_e	126..445	CDD:187547	76/313 (24%)
CG5065	NP_001163168.1	Sterile	472..562	CDD:281068
LYS2	NP_009673.1	alpha_am_amid	7..1379	CDD:274582	76/313 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	51	1.000	Domainoid score	I2873
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.712175	Normalized mean entropy	S3219
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.860