DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5065 and CER4

DIOPT Version :9

Sequence 1:	NP_001163168.1	Gene:	CG5065 / 36860	FlyBaseID:	FBgn0034145	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_567936.5	Gene:	CER4 / 829521	AraportID:	AT4G33790	Length:	493	Species:	Arabidopsis thaliana

Alignment Length:	496	Identity:	136/496 - (27%)
Similarity:	242/496 - (48%)	Gaps:	61/496 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 VPIAQFYAGRSVFITGGTGFMGKVLVEKLLRSCPEIRNIYLLIRPKRGQEVSARLT-ELLNAPLF 180
            |.:.::...:|:.:.|..||:..:.|||:||..|.::.:|||:|..:|:..:.|.. |:|...||
plant     8 VSVLKYLDNKSILVVGAAGFLANIFVEKILRVAPNVKKLYLLLRASKGKSATQRFNDEILKKDLF 72

  Fly   181 ESLRQEKPKELS-----KVIPISGDITSEELGISEKD-QNLLCRNVSVVFHSAATVKFDEKLKLS 239
            :.|:::....|:     |:..:.|||..|:||:.:.| .:.:...|..:.:.|||.||||:..::
plant    73 KVLKEKYGPNLNQLTSEKITIVDGDICLEDLGLQDFDLAHEMIHQVDAIVNLAATTKFDERYDVA 137

  Fly   240 VTINMLGTKRLVELCHRMLSLDALIHVSTAY-CNCDRTDVSEVIYAPPYNPDDIIS-----LINW 298
            :.||.||...::....|...:..|:|||||| |.    :.|.:|...||...:.::     .||:
plant   138 LGINTLGALNVLNFAKRCAKVKILVHVSTAYVCG----EKSGLIMETPYRMGETLNGTTGLDINY 198

  Fly   299 ---LPEDILDQL------------TPRLIGKR-------PNTYTFTKALAEHMLLKEAGNLPVAI 341
               |.::.||||            |.:.:|.|       ||||.||||:.|.|:..:..||.:.:
plant   199 EKKLVQEKLDQLRVIGAAPETITETMKDLGLRRAKMYGWPNTYVFTKAMGEMMVGTKRENLSLVL 263

  Fly   342 VRPSIVTASLNEPFAGWVDNFNGPTGLVSALAKGMFRTMMCEKNYVADMVPVDIVINLMIAAAWR 406
            :||||:|::..|||.||.:.......|.....||.....:|:.:.|:|::|.|:|:|.::.:...
plant   264 LRPSIITSTFKEPFPGWTEGIRTIDSLAVGYGKGKLTCFLCDLDAVSDVMPADMVVNSILVSMAA 328

  Fly   407 TATRKSNNLLIYNCCTGQRNPIIWSEFVKHAMTSVRKHP---LEGCLWYPTGDLRMNRPMNTLNC 468
            .|.::..  :||:..:..|||:..|:|.:.|.......|   .||.: ...|.:.:   ::::..
plant   329 QAGKQEE--IIYHVGSSLRNPMKNSKFPELAYRYFSIKPWTNKEGKV-VKVGAIEI---LSSMRS 387

  Fly   469 IAKHFLPAYI--LDG--VARIMGKKPFVVNVQ------NKIAKAVECLEYFATRQWRFKDDNVHA 523
            ..::....|:  |.|  :..|:..|.|....|      |.|.:.|:..:.:......|.|.|...
plant   388 FHRYMTIRYLIALKGLELVNIILCKLFEKEFQYFNKKINFIFRLVDLYQPYLFFYGIFDDSNTEK 452

  Fly   524 LLHTLSPK--DREIFVFDVRHINWDKY-VERYVLGFREFLF 561
            |...:|..  :.|:|.||.:.::||.| :..:|:|..:::|
plant   453 LRKMVSKTGVENEMFYFDPKVLDWDDYFLNTHVIGLLKYVF 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5065	NP_001163168.1	FAR-N_SDR_e	126..445	CDD:187547	106/353 (30%)
CG5065	NP_001163168.1	Sterile	472..562	CDD:281068	25/103 (24%)
CER4	NP_567936.5	PLN02996	6..493	CDD:215538	135/494 (27%)
		FAR-N_SDR_e	17..365	CDD:187547	106/353 (30%)
		Sterile	396..493	CDD:281068	24/96 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D815047at2759
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	1	0.900	-	-		OOG6_100550
Panther	1	1.100	-	-	O	PTHR11011
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.870