DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5065 and FAR6

DIOPT Version :9

Sequence 1:	NP_001163168.1	Gene:	CG5065 / 36860	FlyBaseID:	FBgn0034145	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_001326776.1	Gene:	FAR6 / 824837	AraportID:	AT3G56700	Length:	548	Species:	Arabidopsis thaliana

Alignment Length:	489	Identity:	142/489 - (29%)
Similarity:	233/489 - (47%)	Gaps:	54/489 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 VPIAQFYAGRSVFITGGTGFMGKVLVEKLLRSCPEIRNIYLLIRPKRGQEVSARL-TELLNAPLF 180
            :.|.:|..|:|..:||.|||:.|||:|||||...||..|:||:|.|..:..:.|| .|::::.||
plant    75 IGIVRFLEGKSYLVTGATGFLAKVLIEKLLRESLEIGKIFLLMRSKDQESANKRLYDEIISSDLF 139

  Fly   181 ESLRQEKPKELS-----KVIPISGDITSEELGISEKDQNLLCRNVSVVFHSAATVKFDEKLKLSV 240
            :.|:|.......     |:||:.|||..:.|||..:..|::...:.|:........||::...::
plant   140 KLLKQMHGSSYEAFMKRKLIPVIGDIEEDNLGIKSEIANMISEEIDVIISCGGRTTFDDRYDSAL 204

  Fly   241 TINMLGTKRLVELCHRMLSLDALIHVSTAYCNCDRTDVSEVIYAPPYNPDDIISLINWLPE-DIL 304
            ::|.||..||:........|...:|.||||....|.  ..|:..|....::|.|.:|...| .:.
plant   205 SVNALGPGRLLSFGKGCRKLKLFLHFSTAYVTGKRE--GTVLETPLCIGENITSDLNIKSELKLA 267

  Fly   305 DQLTPRLIGKR------------------PNTYTFTKALAEHMLLKEAGNLPVAIVRPSIVTASL 351
            .:...:..|:.                  .|:||||||:.|.::..:.|||||.|:||||:.:|.
plant   268 SEAVRKFRGREEIKKLKELGFERAQHYGWENSYTFTKAIGEAVIHSKRGNLPVVIIRPSIIESSY 332

  Fly   352 NEPFAGWVDNFNGPTGLVSALAKGMFRTMMCEKNYVADMVPVDIVINLMIAAAWRTATRKSNNLL 416
            ||||.||:........::.|.|||.......:...:.|::|||:|.|..|||..:...... ...
plant   333 NEPFPGWIQGTRMADPIILAYAKGQISDFWADPQSLMDIIPVDMVANAAIAAMAKHGCGVP-EFK 396

  Fly   417 IYNCCTGQR-NPIIWSEFVKHAMTSVRKHPLEGCLWYPTGDLRMNRPMNTL--------NCIAKH 472
            :||..:... ||:...:.:..:...:...|||..:.    ||...:..::|        |.|.|.
plant   397 VYNLTSSSHVNPMRAGKLIDLSHQHLCDFPLEETVI----DLEHMKIHSSLEGFTSALSNTIIKQ 457

  Fly   473 FLPAYILD---GVARIMGKKPFVVNVQNKIAKAVECLEYFATRQWRFKDDNVHALLHTLSPKDRE 534
               ..::|   |.....||:.  :|....:||..|...:|   |.||.:.|..:|:..:|.::::
plant   458 ---ERVIDNEGGGLSTKGKRK--LNYFVSLAKTYEPYTFF---QARFDNTNTTSLIQEMSMEEKK 514

  Fly   535 IFVFDVRHINWDKY-VERYVLGF-REFLFKQRPE 566
            .|.||::.|:|:.| |..::.|. :|||.|::.|
plant   515 TFGFDIKGIDWEHYIVNVHLPGLKKEFLSKKKTE 548

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5065	NP_001163168.1	FAR-N_SDR_e	126..445	CDD:187547	102/344 (30%)
CG5065	NP_001163168.1	Sterile	472..562	CDD:281068	26/94 (28%)
FAR6	NP_001326776.1	PLN02996	77..539	CDD:215538	137/476 (29%)
		FAR-N_SDR_e	84..426	CDD:187547	102/344 (30%)
		FAR_C	<471..539	CDD:176924	21/72 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D815047at2759
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	1	0.900	-	-		OOG6_100550
Panther	1	1.100	-	-	O	PTHR11011
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.870