DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5065 and FAR8

DIOPT Version :9

Sequence 1:	NP_001163168.1	Gene:	CG5065 / 36860	FlyBaseID:	FBgn0034145	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_190042.2	Gene:	FAR8 / 823581	AraportID:	AT3G44560	Length:	496	Species:	Arabidopsis thaliana

Alignment Length:	516	Identity:	143/516 - (27%)
Similarity:	229/516 - (44%)	Gaps:	130/516 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 FYAGRSVFITGGTGFMGKVLVEKLLRSCPEIRNIYLLIRPKRGQEVSARL-TELLNAPLFESLR- 184
            |...:::.:||.|||:.||.|||:||..|.:..:||::|....:..:.|| ||.....||:.||
plant     8 FLQNKTILVTGATGFLAKVFVEKILRVQPNVNKLYLVVRASDNEAATKRLRTEAFEKDLFKVLRD 72

  Fly   185 ---QEKPKEL--SKVIPISGDITSEELGISEKDQNL---LCRNVSVVFHSAATVKFDEKLKLSVT 241
               .||...|  .||:|::|||..:.||:  ||.||   :.:.:.:|.:.|||..|||:..:.:.
plant    73 NLGDEKLNTLLSEKVVPVAGDIAMDHLGM--KDSNLRERMQKEIDIVVNVAATTNFDERYDIGLG 135

  Fly   242 INMLGTKRLVELCHRMLSLDALIHVSTAY-CNCDRTDVSEVIYAPPYNPDDIISLINWLPEDILD 305
            ||..|...::....:.:....|:|||||| |.    :...::...|:..::|.: .|.|..||
plant   136 INTFGALNVLNFAKKCVKAQLLLHVSTAYVCG----EKPGLLPEKPFVMEEICN-ENGLQLDI-- 193

  Fly   306 QLTPRLIGKR-------------------------------PNTYTFTKALAEHMLLKEAGNLPV 339
            .|...|:.:|                               ||||.|||::.|.:|.....|||:
plant   194 NLERELMKQRLKELNEQGCSEEGTTFYMKELGMERAKLHGWPNTYVFTKSMGEMLLGNHKENLPL 258

  Fly   340 AIVRPSIVTASLNEPFAGWVDNFNGPTGLVSALAKGMFRTMMCEKNYVADMVPVDIVINLMIAAA 404
            .|:||:::|::|.|||.||::.......::.|..||:.:..:.:.|.|.||:|.|:|.|.|||||
plant   259 VIIRPTMITSTLFEPFPGWIEGLRTVDSVIIAYGKGVLKCFLVDVNSVCDMIPADMVANAMIAAA 323

  Fly   405 WRTATRKSNNLLIYNCCTGQRNPIIWSE--------FVKH-------AMTSVRKHPLEGCLWYPT 454
             .|....|...::|...:..:||||:.|        |.|:       :|.:|.|..|     .||
plant   324 -ATHAGGSKVHMVYQVGSSHQNPIIYGEIREILFCYFTKNSLRSRNGSMITVSKMKL-----IPT 382

  Fly   455 GDLRMNRPMNTLNCIAKHFLPAYIL----------------------DGVARIMG-KKPFVV--- 493
                  ..:.:|....::.||..:|                      |.|.|::. .:|:|:
plant   383 ------LALFSLYMTIRYKLPVQLLKLVDIIYPSREGDEYKNKNRKIDMVMRLVKLYEPYVLFKG 441

  Fly   494 -----NVQNKIAKAVECLEYFATRQWRFKDDNVHALLHTLSPKDREIFVFDVRHINWDKYV 549
                 |.:|..||..|             :||.::        :..:|.||.:.|.|..|:
plant   442 IFDDRNTKNLCAKQKE-------------EDNRNS--------ENFMFDFDPKIIKWKDYL 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5065	NP_001163168.1	FAR-N_SDR_e	126..445	CDD:187547	117/375 (31%)
CG5065	NP_001163168.1	Sterile	472..562	CDD:281068	21/109 (19%)
FAR8	NP_190042.2	PLN02996	1..495	CDD:215538	143/516 (28%)
		FAR-N_SDR_e	12..362	CDD:187547	113/359 (31%)
		Sterile	394..495	CDD:281068	21/109 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D815047at2759
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	1	0.900	-	-		OOG6_100550
Panther	1	1.100	-	-	O	PTHR11011
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.870