DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5065 and MS2

DIOPT Version :9

Sequence 1:	NP_001163168.1	Gene:	CG5065 / 36860	FlyBaseID:	FBgn0034145	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_187805.1	Gene:	MS2 / 820372	AraportID:	AT3G11980	Length:	616	Species:	Arabidopsis thaliana

Alignment Length:	624	Identity:	155/624 - (24%)
Similarity:	265/624 - (42%)	Gaps:	114/624 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 NGTLARTNGLT----HAA-SVATSSSGSYGSSSAAGSNAGSGGPTSSASLSI------------- 83
            :.::..:|.||    |.. |........:|.:.......|.||..|:|...|
plant    10 SSSIVASNKLTRLHNHCVWSTVIRDKKRFGPTWCRVGGGGDGGRNSNAERPIRVSSLLKDRGQVL 74

  Fly    84 ----AAGVASSTALPLPPSSNG---------LQMPYERFRADDTSYV------PIAQFYAGRSVF 129
                ::....:..|.|.|:.||         ..||:     ...|.|      .|..|..|:...
plant    75 IREQSSPAMDAETLVLSPNGNGRTIEINGVKTLMPF-----SGASMVGMKEGLGIISFLQGKKFL 134

  Fly   130 ITGGTGFMGKVLVEKLLRSCPEIRNIYLLIRPKRGQEVSARL-TELLNAPLFESLRQEKPKE--- 190
            |||.|||:.|||:||:||..|::..|||||:.|..:....|| .|:|:|.||.:|::.....
plant   135 ITGSTGFLAKVLIEKVLRMAPDVSKIYLLIKAKSKEAAIERLKNEVLDAELFNTLKETHGASYMS 199

  Fly   191 --LSKVIPISGDITSEELGISEKDQNLLCRNVSVVFHSAATVKFDEKLKLSVTINMLGTKRLVEL 253
              |:|:||::|:|....:|:.......:.:.|.|:.:|||...|:|:..:::.||..|...|:..
plant   200 FMLTKLIPVTGNICDSNIGLQADSAEEIAKEVDVIINSAANTTFNERYDVALDINTRGPGNLMGF 264

  Fly   254 CHRMLSLDALIHVSTAYCNCDRTDVSEVIYAPPYNPDDIISLINWLPE-----DILDQLTPRLIG 313
            ..:...|...:.|||||.|..|   ...|...|::..|.|:..|:|..     |:..::...|..
plant   265 AKKCKKLKLFLQVSTAYVNGQR---QGRIMEKPFSMGDCIATENFLEGNRKALDVDREMKLALEA 326

  Fly   314 KR-------------------------PNTYTFTKALAEHMLLKEAGNLPVAIVRPSIVTASLNE 353
            .|                         .:||.||||:.|.|:....|::||.|:|||::.::..:
plant   327 ARKGTQNQDEAQKMKDLGLERARSYGWQDTYVFTKAMGEMMINSTRGDVPVVIIRPSVIESTYKD 391

  Fly   354 PFAGWVDNFNGPTGLVSALAKGMFRTMMCEKNYVADMVPVDIVINLMIAAAWRTATRKSN---NL 415
            ||.||::.......:|....||.....:.:...|.|:||.|:|:|..:||..:.....|:   .:
plant   392 PFPGWMEGNRMMDPIVLCYGKGQLTGFLVDPKGVLDVVPADMVVNATLAAIAKHGMAMSDPEPEI 456

  Fly   416 LIYNCCTGQRNPIIWSEFVKHAMTSVRKHPLEGCLWYPTGD---LRMNRPMNTLNCIAKHFL--- 474
            .:|...:...||:::.:..:......:..|   |: ...||   :|:.:..|:::..:.|..
plant   457 NVYQIASSAINPLVFEDLAELLYNHYKTSP---CM-DSKGDPIMVRLMKLFNSVDDFSDHLWRDA 517

  Fly   475 --PAYILDGV----ARIMGKKPFVVNVQNKIAKAVECLEYFAT-------RQWRFKDDNVHALLH 526
              .:.::.|:    :::|.|..|:..      |:||..::.||       ...||.:.|...|:.
plant   518 QERSGLMSGMSSVDSKMMQKLKFICK------KSVEQAKHLATIYEPYTFYGGRFDNSNTQRLME 576

  Fly   527 TLSPKDREIFVFDVRHINWDKYVER-YVLGFREFLFKQR 564
            .:|..::..|.|||..|||..|:.. ::.|.|..:.|.|
plant   577 NMSEDEKREFGFDVGSINWTDYITNVHIPGLRRHVLKGR 615

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5065	NP_001163168.1	FAR-N_SDR_e	126..445	CDD:187547	98/357 (27%)
CG5065	NP_001163168.1	Sterile	472..562	CDD:281068	25/106 (24%)
MS2	NP_187805.1	PLN02503	1..616	CDD:215279	155/624 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H69247
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D815047at2759
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	1	0.900	-	-		OOG6_100550
Panther	1	1.100	-	-	O	PTHR11011
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.870