DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5065 and CG4770

DIOPT Version :9

Sequence 1:	NP_001163168.1	Gene:	CG5065 / 36860	FlyBaseID:	FBgn0034145	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_650848.1	Gene:	CG4770 / 42375	FlyBaseID:	FBgn0038751	Length:	490	Species:	Drosophila melanogaster

Alignment Length:	479	Identity:	163/479 - (34%)
Similarity:	272/479 - (56%)	Gaps:	11/479 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 YAGRSVFITGGTGFMGKVLVEKLLRSCPEIRNIYLLIRPKRGQEVSARLTELLNAPLFESLRQEK 187
            |....|||||.|||:||.|:||||.|.|:|:.||:|||||.|..|..|....|..|:||.::.|.
  Fly    16 YQDAVVFITGATGFVGKSLLEKLLWSFPQIKRIYMLIRPKGGVTVEERFRGFLQNPIFERIKSEH 80

  Fly   188 PKELSKVIPISGDITSEELGISEKDQNLLCRNVSVVFHSAATVKFDEKLKLSVTINMLGTKRLVE 252
            |.:|.|:...||:|..:.||::|.|:::||..|:::|||||||:|:|.||:|..:|...|..|:|
  Fly    81 PTQLKKIFHFSGNIEDDNLGLNESDRSVLCAEVNIIFHSAATVRFNECLKVSARVNSQATYNLLE 145

  Fly   253 LCHRMLSLDALIHVSTAYCNCDRTDVSEVIY--APPYNPDDIISLINWLPEDILDQLTPRLIGKR 315
            ||.:|..|.:.::|||||||..|..|.|.:|  .||.:....:|....:|:|.|::|...:.|..
  Fly   146 LCRQMPYLRSFLYVSTAYCNPGRKYVDEQVYPTMPPVDWRQFLSATQKIPDDYLNRLADYIKGPH 210

  Fly   316 PNTYTFTKALAEHMLLKEAGNLPVAIVRPSIVTASLNEPFAGWVDNFNGPTGLVSALAKGMFRTM 380
            .|||||||::||.::......:|:.|||||||||:..||:.||:||....:|::..:.||...::
  Fly   211 VNTYTFTKSIAEQIVNAYKDVIPIVIVRPSIVTAAYREPYPGWIDNIQAISGIMMEIGKGGISSI 275

  Fly   381 MCEKNYVADMVPVDIVINLMIAAAWRTATRKSNNLLIYNCCTGQRNPIIWSEFVKHAMTSVRKHP 445
            :..|:.:.|::|||.|:|.||....:.   |..:|.|.|..:|..|||.|....:..|...|.:|
  Fly   276 LGNKDLICDIIPVDFVVNAMIMMVGKA---KLGSLSICNATSGVTNPITWQHLGELTMKWSRIYP 337

  Fly   446 LEGCLWYPTGDLRMNRPMNTLNCIAKHFLPAYILDGVARIMG-KKPFVVNVQNKIAKAVECLEYF 509
            ....:.:|....|.:...:.|.....||:||.::|....::. ||..|..:..|..:|.....:|
  Fly   338 TRRMIMFPNFKYRCSAFNHELAVWVLHFVPALLMDLQTLLLAQKKRLVTPIAKKFRQACLAGSFF 402

  Fly   510 ATRQWRFKDDNVHALLHTLSPKDREIFVFDVRHINWDKYVERYVLGFREFLFKQRPESLPASRKR 574
            :..:|.||:.:.......:.........:::..:::|:||.|:::|..::|.::: .::.:::..
  Fly   403 SLNEWIFKNKSRFYFKEMIENGTYPTLYWNLEEMDYDEYVRRHMIGINKYLHREK-FTVDSNKFM 466

  Fly   575 MLRLY----YLHQLTKLVAVLLTW 594
            :.|:|    :||.:..::.|.:::
  Fly   467 VTRIYWFWIFLHLMFYMMLVYISF 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5065	NP_001163168.1	FAR-N_SDR_e	126..445	CDD:187547	133/320 (42%)
CG5065	NP_001163168.1	Sterile	472..562	CDD:281068	20/90 (22%)
CG4770	NP_650848.1	WcaG	21..358	CDD:223528	136/339 (40%)
		FAR-N_SDR_e	21..337	CDD:187547	133/318 (42%)
		Sterile	364..455	CDD:281068	20/90 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466827
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28069
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
	11	10.910