DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5065 and Sgp

DIOPT Version :9

Sequence 1:	NP_001163168.1	Gene:	CG5065 / 36860	FlyBaseID:	FBgn0034145	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_001260257.1	Gene:	Sgp / 34188	FlyBaseID:	FBgn0032055	Length:	523	Species:	Drosophila melanogaster

Alignment Length:	497	Identity:	176/497 - (35%)
Similarity:	280/497 - (56%)	Gaps:	27/497 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 IAQFYAGRSVFITGGTGFMGKVLVEKLLRSCPEIRNIYLLIRPKRGQEVSARLTELLNAPLFESL 183
            |.|||..:|||:||||||:|||::|||||| .::|.:|||:|||:.:.|..|.....:.|:|:.|
  Fly     5 ILQFYKDKSVFVTGGTGFLGKVIIEKLLRS-TDVRRVYLLVRPKKNETVEGRFQAWKDEPVFKIL 68

  Fly   184 RQEKPKELSKVIPISGDITSEELGISEKDQNLLCRNVSVVFHSAATVKFDEKLKLSVTINMLGTK 248
            .:.||:.|..|.|||||.:...||:|:.|:.::..:|.|:.||||:::|.|.|:.::.||...|:
  Fly    69 LKAKPEALKLVTPISGDCSEPGLGLSDGDRRMVTADVQVIIHSAASIRFVEPLQRALNINTRATR 133

  Fly   249 RLVELCHRMLSLDALIHVSTAYCNCDRTDVSEVIYAPPYNPD-------DIISLINWLPEDILDQ 306
            .:::|...|..|:|.:|:|||:.||....:.|..|     |:       .::.....|..|:||:
  Fly   134 LMIQLAKEMKGLEAFVHISTAFSNCPSQHIEERFY-----PEHLTCPAAKVLEFNETLSPDLLDK 193

  Fly   307 LTPRLIGKRPNTYTFTKALAEHMLLKEAGNLPVAIVRPSIVTASLNEPFAGWVDNFNGPTGLVSA 371
            :.|.|:||.|||||:||||||.::..|..:||:.:.||:|:.|:..||.:||:||.:|...|:..
  Fly   194 MAPALMGKFPNTYTYTKALAEQVIQMEGQDLPICVFRPAIILANFKEPMSGWIDNLHGVVALIYG 258

  Fly   372 LAKGMFRTMMCEKNYVADMVPVDIVINLMIAAAWRTA----TRKSNNLL------IYNCCTGQRN 426
            ...|:.|.:.......|.:||.|...|:.:|:.|:.|    :|.|:.|.      ||...|.:.|
  Fly   259 NTYGILRLLYVNPKADAIIVPGDYCANVALASGWQVAKNSESRSSSQLAAKKPPPIYTLATTKSN 323

  Fly   427 PIIWSEFVKHAMTSVRKHPLEGCLWYPTGDLRMNRPMNTLNCIAKHFLPAYILDGVARIMGKKPF 491
            .|.:.:.||..:......|:...:|||.........:..|.||..|.:|.:..|.:.||.||||.
  Fly   324 SITFGKAVKLGIHHNHTIPVTKTIWYPFAHFTTCPWLFKLGCIFYHLIPGFFFDLLLRIQGKKPI 388

  Fly   492 VVNVQNKIAKAVECLEYFATRQWRFKDDNVHALLHTLSPKDREIFVFDVRHINWDKYVERYVLGF 556
            ::....||.:.:..|..|..:.:....:|.:.|..::||:||.||.||:..:||::|..|.:.|.
  Fly   389 LMRSYQKIHEVLLLLFPFNGKTYEMDMNNTNQLWDSMSPEDRSIFPFDMATLNWEEYFTRILSGM 453

  Fly   557 REFLFKQRPESLPASRKRMLRLYYLHQLTKLVAVL----LTW 594
            |.||:|:..::|..::||:.|.|.||:..:||..|    :.|
  Fly   454 RVFLYKESWDTLEQAKKRLFRFYILHRSLQLVLCLALGKIVW 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5065	NP_001163168.1	FAR-N_SDR_e	126..445	CDD:187547	122/335 (36%)
CG5065	NP_001163168.1	Sterile	472..562	CDD:281068	31/89 (35%)
Sgp	NP_001260257.1	PLN02996	1..449	CDD:215538	159/449 (35%)
		FAR-N_SDR_e	12..333	CDD:187547	121/326 (37%)
		FAR_C	367..457	CDD:176924	29/89 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466830
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
	10	9.900