DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5065 and far1

DIOPT Version :9

Sequence 1:	NP_001163168.1	Gene:	CG5065 / 36860	FlyBaseID:	FBgn0034145	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	XP_017948360.1	Gene:	far1 / 100038270	XenbaseID:	XB-GENE-973776	Length:	518	Species:	Xenopus tropicalis

Alignment Length:	495	Identity:	205/495 - (41%)
Similarity:	323/495 - (65%)	Gaps:	3/495 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 VPIAQFYAGRSVFITGGTGFMGKVLVEKLLRSCPEIRNIYLLIRPKRGQEVSARLTELLNAPLFE 181
            :.|.:||.|::|.|||.||||||||:||||||||.::.:|:|:|||..|:...|:.|:::..||:
Frog     2 ISIPEFYRGKNVLITGATGFMGKVLLEKLLRSCPNVKAVYVLVRPKASQKPRERVAEMMSCKLFD 66

  Fly   182 SLRQEKPKELSKVIPISGDITSEELGISEKDQNLLCRNVSVVFHSAATVKFDEKLKLSVTINMLG 246
            .||.|:|:...|||.||.::|..||.:|::||::|...:.:|||.||||:|:|.|:.::.:|::.
Frog    67 RLRDEQPECAQKVIAISSELTQPELDLSKEDQDMLIDCIDIVFHCAATVRFNESLRDAMQLNVIA 131

  Fly   247 TKRLVELCHRMLSLDALIHVSTAYCNCDRTDVSEVIYAPPYNPDDIISLINWLPEDILDQLTPRL 311
            |::|:.|..::..|:..|||||||.||:|..:.|::|.||.:|..:|..:.|:.:.:::.:||:|
Frog   132 TRQLLYLAQKIKKLEVFIHVSTAYANCNRKQIEEMVYPPPVDPKKLIESLEWMDDGLVNDITPKL 196

  Fly   312 IGKRPNTYTFTKALAEHMLLKEAGNLPVAIVRPSIVTASLNEPFAGWVDNFNGPTGLVSALAKGM 376
            ||.||||||:||||||:::.:|...|.:||||||||.||..|||.||:||||||:||..|..||:
Frog   197 IGDRPNTYTYTKALAEYVVQQEGSKLNIAIVRPSIVGASWKEPFPGWIDNFNGPSGLFIAAGKGI 261

  Fly   377 FRTMMCEKNYVADMVPVDIVINLMIAAAWRTATR---KSNNLLIYNCCTGQRNPIIWSEFVKHAM 438
            .|||....|.|||::|||:|:|..:||||.:...   :..|:|:|||.||..||..|.|...|.:
Frog   262 LRTMRASNNAVADLIPVDVVVNTTLAAAWYSGVNRYSRPRNILVYNCTTGGTNPFHWGEVEYHVI 326

  Fly   439 TSVRKHPLEGCLWYPTGDLRMNRPMNTLNCIAKHFLPAYILDGVARIMGKKPFVVNVQNKIAKAV 503
            ::.:::|||.....|..:|..|..:........|..||::.|...||.|:.|.::....::.||:
Frog   327 STFKRNPLEQAFRRPNVNLTSNHLLYHYWIAVSHKAPAFLYDVYLRITGRSPRMMKTITRLHKAM 391

  Fly   504 ECLEYFATRQWRFKDDNVHALLHTLSPKDREIFVFDVRHINWDKYVERYVLGFREFLFKQRPESL 568
            ..||||.:..|.:.::|.:.|:..|||.|::.|.||||.::|.:|:|.|.:|.::::..:....|
Frog   392 MLLEYFTSNSWVWNNENTNMLMSQLSPDDKKAFNFDVRQLHWAEYMENYCMGTKKYVLNEEMSGL 456

  Fly   569 PASRKRMLRLYYLHQLTKLVAVLLTWRFLMSRSKRLNDLW 608
            ||:||.:.:|..:......:.|:|.||..::||:...::|
Frog   457 PAARKHLNKLRNIRYGFNTILVVLIWRVFIARSQMARNIW 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5065	NP_001163168.1	FAR-N_SDR_e	126..445	CDD:187547	151/321 (47%)
CG5065	NP_001163168.1	Sterile	472..562	CDD:281068	31/89 (35%)
far1	XP_017948360.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	297	1.000	Domainoid score	I1452
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	451	1.000	Inparanoid score	I1574
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		oto102204
Panther	1	1.100	-	-	O	PTHR11011
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4354
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	10.100