DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8303 and CG17560

DIOPT Version :9

Sequence 1:	NP_001286495.1	Gene:	CG8303 / 36858	FlyBaseID:	FBgn0034143	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_650567.1	Gene:	CG17560 / 42022	FlyBaseID:	FBgn0038450	Length:	499	Species:	Drosophila melanogaster

Alignment Length:	518	Identity:	142/518 - (27%)
Similarity:	228/518 - (44%)	Gaps:	60/518 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 IPEFFAHKNIFVTGGTGFLGTVLIEALLDTHPDIGTIYVLVRGKRKFDPNERIRRLLQKPIFE-- 101
            |..||.:|.:|:||||||||.|:||.||.| .::..||.|:|.||.....:||....:.|:||
  Fly     5 IQGFFKNKTVFLTGGTGFLGKVIIEKLLRT-TEVNRIYSLIRPKRGVPIEDRITTWAKDPVFEVL 68

  Fly   102 -KYSEKTLSKVVPVVGELSEPNFGFGPELLQELIDRVNVIYHSAATIKFSSPLRTAIRTNLTGTM 165
             :.....|.:|.|:.|:..:|:.|......:.|...|.::.|.|||::|...|..::..|:..|.
  Fly    69 LRTKPDALQRVCPIAGDCLDPDLGISQSDQRILTAEVQIVIHGAATVRFDEALHISLAINVRATR 133

  Fly   166 RTIELAKQLKQLAAYIYCSTAFCNSNNRGLIAEEVYKSQFDPYEMMKMAEDDSAWEDFTDQKCKG 230
            ..::||||:.||.::::.|||:.|..... |||..|....:......:|..:.......|.....
  Fly   134 LMLQLAKQMTQLVSFVHVSTAYSNCVVHD-IAERFYPEHLNCSSDKILAVGELVSNKLLDAMEPS 197

  Fly   231 YIRDHPNTYTFTKNLSENLLMAEMSGLPAAIVRPSIVYGTLEHPMKGWVGNANSGHLGFLAGFVK 295
            .:...|||||:||.|:|::::.|...||.:|.||:|:..|.:.|:.|||.|. .|.|....|..:
  Fly   198 LVGSFPNTYTYTKALAEDVILREAGNLPLSIFRPAIIMSTYKEPLVGWVDNL-FGPLALCFGGAR 261

  Fly   296 GIFRTMCGNANAVIDIIPCDYVINSSLVMGW-----YVGTRKLEQPEIIHCTSGEVNPLNLAEF- 354
            ||.|....:.:|.|.::|.||.:|.:|...|     .|...|:..|.|......|.|.::...|
  Fly   262 GIMRVTTVDPSAKISLVPADYCVNVALACAWRTAEISVQNGKVTTPPIYAFAPSENNLMSYGNFI 326

  Fly   355 --CTIINDSVERHPPNSFVWKP------VTKLRNGWRYNLFFYLFHLLPAMVFIIPEKLFGIGMP 411
              ..|..|.:   |....:|.|      .|.|     :.|..:..|.||...|.:..:|.|   .
  Fly   327 KSSIIYRDII---PLTKMLWYPFVLCISTTSL-----FPLAAFFLHTLPGYFFDLLLRLKG---R 380

  Fly   412 QHTAYEYMRVFQKGTKAFDYFLDKDFRYSLKNALRISALIPESDRRRYNFDASQCDWSEFIDRCL 476
            :....:..|...|.......|....:.:.:.|.:.:...:.:.||..|:||.:|.||:::....:
  Fly   381 KPILVDLYRKIHKNIAVLGPFSSTTWNFDMTNTMELREAMSKQDRNLYDFDMAQLDWNDYFKAAM 445

  Fly   477 IGIRRFYFKESAVTTDWHRNYWKVFNVLYYAGYVVIFAVLYFALTLTLGLQIGLTLAVLIWGF 539
            .|:|.:..||...                             |.::..||::.:.|.||.:.|
  Fly   446 YGMRLYIGKEKPT-----------------------------AESIAKGLKLRMRLKVLHYAF 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8303	NP_001286495.1	FAR-N_SDR_e	46..366	CDD:187547	104/330 (32%)
CG8303	NP_001286495.1	Sterile	392..485	CDD:281068	20/92 (22%)
CG17560	NP_650567.1	PLN02996	1..441	CDD:215538	131/449 (29%)
		FAR-N_SDR_e	12..327	CDD:187547	102/317 (32%)
		Sterile	364..454	CDD:281068	20/92 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466797
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	8.000