DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8306 and CER4

DIOPT Version :9

Sequence 1:	NP_611140.3	Gene:	CG8306 / 36857	FlyBaseID:	FBgn0034142	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_567936.5	Gene:	CER4 / 829521	AraportID:	AT4G33790	Length:	493	Species:	Arabidopsis thaliana

Alignment Length:	508	Identity:	142/508 - (27%)
Similarity:	219/508 - (43%)	Gaps:	84/508 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ITDFYAGRNVFITGATGFVGVTIVEKLLRDVPNVGTLYLLMRAKKGKSVQERL-EELKKNSVFDK 69
            :..:...:::.:.||.||:....|||:||..|||..||||:||.||||..:|. :|:.|..:|..
plant    10 VLKYLDNKSILVVGAAGFLANIFVEKILRVAPNVKKLYLLLRASKGKSATQRFNDEILKKDLFKV 74

  Fly    70 FKEL------QLQSRLSKIVPIEGDVGLEHLGISPKD-RQTLIDNVNVVFHSAATLDFFQSLKET 127
            .||.      ||.|  .||..::||:.||.||:...| ...:|..|:.:.:.|||..|.:.....
plant    75 LKEKYGPNLNQLTS--EKITIVDGDICLEDLGLQDFDLAHEMIHQVDAIVNLAATTKFDERYDVA 137

  Fly   128 TNINLRGTRRVVELCQQIKNLDALVHVSSAYV---------------------------NAYLTK 165
            ..||..|...|:...::...:..|||||:|||                           |.....
plant   138 LGINTLGALNVLNFAKRCAKVKILVHVSTAYVCGEKSGLIMETPYRMGETLNGTTGLDINYEKKL 202

  Fly   166 VEEKL------YPAPEDPEKIIQLSETLNDDALKELEPKLLKDHPNTYTFTKHLAEHEVANVASK 224
            |:|||      ..|||      .::||:.|..|:..:   :...||||.|||.:.|..|......
plant   203 VQEKLDQLRVIGAAPE------TITETMKDLGLRRAK---MYGWPNTYVFTKAMGEMMVGTKREN 258

  Fly   225 FPCGIVRPSMITAAWKEPIPGWTISKNGPQGFFMGASKGVLRRLPLDPSIIMDYIPIDVVVNGII 289
            ....::|||:||:.:|||.||||..........:|..||.|.....|...:.|.:|.|:|||.|:
plant   259 LSLVLLRPSIITSTFKEPFPGWTEGIRTIDSLAVGYGKGKLTCFLCDLDAVSDVMPADMVVNSIL 323

  Fly   290 TTGYYVNSLQAKNGGRPADLQIFHLTSSTYKPFRFELMTDKINSYLHDYPLNS----AVWYPNLR 350
            .:       .|...|:..:: |:|:.||...|.:.....:....|....|..:    .|....:.
plant   324 VS-------MAAQAGKQEEI-IYHVGSSLRNPMKNSKFPELAYRYFSIKPWTNKEGKVVKVGAIE 380

  Fly   351 LVKSLWVFRLSAILFHFIPAIILDLVTKIGGGRPILVRLHKNVWNSLNTLEKFIF--TEWH---- 409
            ::.|:..|.....:.:.|....|:||      ..||.:|.:..:...|....|||  .:.:
plant   381 ILSSMRSFHRYMTIRYLIALKGLELV------NIILCKLFEKEFQYFNKKINFIFRLVDLYQPYL 439

  Fly   410 -----FDSKRLLALSKTLNI--VDKKKFFIDIGELAWDEYFSNT-ILGVRQYL 454
                 ||......|.|.::.  |:.:.|:.|...|.||:||.|| ::|:.:|:
plant   440 FFYGIFDDSNTEKLRKMVSKTGVENEMFYFDPKVLDWDDYFLNTHVIGLLKYV 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8306	NP_611140.3	PLN02996	6..456	CDD:215538	142/508 (28%)
		FAR-N_SDR_e	13..339	CDD:187547	111/366 (30%)
		FAR_C	364..454	CDD:176924	26/103 (25%)
CER4	NP_567936.5	PLN02996	6..493	CDD:215538	142/508 (28%)
		FAR-N_SDR_e	17..365	CDD:187547	111/366 (30%)
		Sterile	396..493	CDD:281068	27/103 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
OMA	1	1.010	-	-		QHG56516
OrthoDB	1	1.010	-	-		D815047at2759
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11011
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.940