DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8306 and FAR4

DIOPT Version :9

Sequence 1:	NP_611140.3	Gene:	CG8306 / 36857	FlyBaseID:	FBgn0034142	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_190040.3	Gene:	FAR4 / 823579	AraportID:	AT3G44540	Length:	493	Species:	Arabidopsis thaliana

Alignment Length:	530	Identity:	138/530 - (26%)
Similarity:	227/530 - (42%)	Gaps:	125/530 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 FYAGRNVFITGATGFVGVTIVEKLLRDVPNVGTLYLLMRAKKGKSVQERL--EELKKNSVFDKFK 71
            |...:.:.:||..||:....|||:||..|.|..|:||:||...:|..:|.  |.|:|    |.|:
plant     8 FLHDKTILVTGVPGFLAKVFVEKILRIQPKVKKLFLLLRAADNESAMQRFHSEVLEK----DLFR 68

  Fly    72 ELQ-------LQSRLS-KIVPIEGDVGLEHLGISPKD-RQTLIDNVNVVFHSAATLDFFQSLKET 127
            .|:       |::.:: |:|||.||:.:::||:...| .|.:.:.::::.:.|||.:|.:.....
plant    69 VLKNALGDENLKAFITEKVVPIPGDISVDNLGVKGSDLLQHMWNEIDIIVNVAATTNFDERYDVG 133

  Fly   128 TNINLRGTRRVVELCQQIKNLDALVHVSSAYVNAYLTKVEEK---LYPAPEDPEKIIQLSETLN- 188
            .::|..|...|:...::......|:|||:|||..      ||   |:      ||...:.||||
plant   134 LSVNTFGPLNVLNFAKKCVKGQLLLHVSTAYVRG------EKSGLLH------EKTFHMGETLNG 186

  Fly   189 -------------DDALKELE---------PKLLKD--------H--PNTYTFTKHLAEHEVANV 221
                         ...||||:         .:.:||        |  ||||.|||.:.|..:.|.
plant   187 HRKLVIETEMELMKQKLKELQKQNCSEEEISQSMKDLGMSRAKLHGWPNTYVFTKSMGEMLLGNY 251

  Fly   222 ASKFPCGIVRPSMITAAWKEPIPGWTISKNGPQGFFMGASKGVLRRLPLDPSIIMDYIPIDVVVN 286
            ....|..|:||:|||:.:.||.|||...........:...||.|:....||:.::|.||:|:|.|
plant   252 RENLPIVIIRPTMITSTFSEPFPGWIEGLRTIDSVIVAYGKGRLKCFLADPNSVLDLIPVDMVAN 316

  Fly   287 GIITTGYYVNSLQAKNGGRPADLQIFHLTSSTYKPFRFELMTDKINSYLHDYPL----NSAV--- 344
            .::|..       |.:.|:.....::|:.||...|..||.:.|...||....||    .|::
plant   317 AMVTAA-------AIHAGKLGSQTVYHVGSSCKNPITFEQIHDLAASYFTKNPLVRRDGSSILVS 374

  Fly   345 ------------WYPNLRLVKSLWVFRLSAILFHF--------------IPAIILDLVTKIGGGR 383
                        :|..||....|.:.||..:::.:              :...::||.      |
plant   375 KGTILSTMAQFSFYMTLRYKLPLQMLRLIYVIYPWWNGNKYKDIDRKIKLAMRLVDLY------R 433

  Fly   384 PILVRLHKNVWNSLNTLEKFIFTEWHFDSKRLLALSKTLNIVDKKKFFIDIGELAWDEYFSNT-I 447
            |.:  |.|.:::..||             ::|....|.:|......|..|...:.|::|.:.. |
plant   434 PYV--LFKGIFDDTNT-------------EKLRLKRKEINKEMYGLFEFDPKSIDWEDYMTTIHI 483

  Fly   448 LGVRQYLSKE 457
            .|:..|:.|:
plant   484 PGLITYVLKK 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8306	NP_611140.3	PLN02996	6..456	CDD:215538	137/527 (26%)
		FAR-N_SDR_e	13..339	CDD:187547	109/372 (29%)
		FAR_C	364..454	CDD:176924	17/104 (16%)
FAR4	NP_190040.3	PLN02996	1..492	CDD:215538	137/527 (26%)
		FAR-N_SDR_e	12..362	CDD:187547	109/372 (29%)
		Sterile	393..492	CDD:281068	21/119 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
OMA	1	1.010	-	-		QHG56516
OrthoDB	1	1.010	-	-		D815047at2759
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11011
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.940