DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8306 and Far1

DIOPT Version :9

Sequence 1:	NP_611140.3	Gene:	CG8306 / 36857	FlyBaseID:	FBgn0034142	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_001272760.1	Gene:	Far1 / 67420	MGIID:	1914670	Length:	515	Species:	Mus musculus

Alignment Length:	522	Identity:	178/522 - (34%)
Similarity:	297/522 - (56%)	Gaps:	30/522 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MASSPITDFYAGRNVFITGATGFVGVTIVEKLLRDVPNVGTLYLLMRAKKGKSVQERLEELKKNS 65
            |.|.|  ::|.|:|:.:||||||:|..::|||||..|.|.::|:|:|.|.|::.|||:||:..:.
Mouse     1 MVSIP--EYYEGKNILLTGATGFLGKVLLEKLLRSCPRVNSVYVLVRQKAGQTPQERVEEILSSK 63

  Fly    66 VFDKFKELQLQSRLSKIVPIEGDVGLEHLGISPKDRQTLIDNVNVVFHSAATLDFFQSLKETTNI 130
            :||:.::.....| .||:.|..::....|.:|.:|::.:||:.||:||.|||:.|.::|::...:
Mouse    64 LFDRLRDENPDFR-EKIIAINSELTQPKLALSEEDKEIIIDSTNVIFHCAATVRFNENLRDAVQL 127

  Fly   131 NLRGTRRVVELCQQIKNLDALVHVSSAYVNAYLTKVEEKLYPAPEDPEKIIQLSETLNDDALKEL 195
            |:..||:::.|.||:|||:..:|||:||.......::|.:||.|.||:|:|...|.::|..:.::
Mouse   128 NVIATRQLILLAQQMKNLEVFMHVSTAYAYCNRKHIDEVVYPPPVDPKKLIDSLEWMDDGLVNDI 192

  Fly   196 EPKLLKDHPNTYTFTKHLAEHEVANVASKFPCGIVRPSMITAAWKEPIPGWTISKNGPQGFFMGA 260
            .|||:.|.||||.:||.|||:.|....:|....|||||::.|:||||.|||..:.|||.|.|:.|
Mouse   193 TPKLIGDRPNTYIYTKALAEYVVQQEGAKLNVAIVRPSIVGASWKEPFPGWIDNFNGPSGLFIAA 257

  Fly   261 SKGVLRRLPLDPSIIMDYIPIDVVVNGIITTGYY--VNSLQAKNGGRPADLQIFHLTSSTYKPFR 323
            .||:||.:....:.:.|.:|:|||||..:...:|  ||        ||.::.:::.|:.:..||.
Mouse   258 GKGILRTMRASNNALADLVPVDVVVNTSLAAAWYSGVN--------RPRNIMVYNCTTGSTNPFH 314

  Fly   324 FELMTDKINSYLHDYPLNSAVWYPNLRLVKSLWVFRLSAILFHFIPAIILDLVTKIGGGRP---- 384
            :..:.|.:|......|||....:|.::...:..:......:.|.:||::|||..::.|.:|
Mouse   315 WGEVGDYLNHSFKMNPLNQVFRHPYVKFCSNNLMLHYWKGVKHTVPALLLDLALRLTGQKPWMMK 379

  Fly   385 ILVRLHKNVWNSLNTLEKFIFTEWHFDSKRLLALSKTLNIVDKKKFFIDIGELAWDEYFSNTILG 449
            .:.||||    ::..||.|....|.:::..:..|...||..|||.|.||:.:|.|.||..|..:|
Mouse   380 TITRLHK----AMVFLEYFTSNSWVWNTDNVNMLMNQLNPEDKKTFNIDVRQLHWAEYIENYCMG 440

  Fly   450 VRQYLSKEPIKNLEKARRKDKILLGLHVALQLSFWYGVFKLIVCLT-GISTAKAALVLPVLYYLF 513
            .::|:..|.:..|..||:        |:....:..||...::|.|. .|..|::.:...:.|::.
Mouse   441 TKKYVLNEEMSGLPAARK--------HLNKLRNIRYGFNTILVILIWRIFIARSQMARNIWYFVV 497

  Fly   514 GL 515
            .|
Mouse   498 SL 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8306	NP_611140.3	PLN02996	6..456	CDD:215538	162/455 (36%)
		FAR-N_SDR_e	13..339	CDD:187547	124/327 (38%)
		FAR_C	364..454	CDD:176924	31/93 (33%)
Far1	NP_001272760.1	FAR-N_SDR_e	11..330	CDD:187547	124/327 (38%)
Far1	NP_001272760.1	Sterile	371..447	CDD:376978	26/79 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847918
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3320
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56516
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.860