DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8306 and CG34342

DIOPT Version :9

Sequence 1:	NP_611140.3	Gene:	CG8306 / 36857	FlyBaseID:	FBgn0034142	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_001097509.3	Gene:	CG34342 / 5740152	FlyBaseID:	FBgn0085371	Length:	572	Species:	Drosophila melanogaster

Alignment Length:	510	Identity:	153/510 - (30%)
Similarity:	269/510 - (52%)	Gaps:	34/510 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MASSPITDFYAGRNVFITGATGFVGVTIVEKLLRDVPNVGTLYLLMRAKKGKSVQERLEELKKNS 65
            ::::|:||||:...|.|||.|||||..:.|||||.. .:..:|:|:|:|...||||||:.....|
  Fly    65 VSATPVTDFYSNATVLITGGTGFVGKVLTEKLLRSF-GLRKIYMLIRSKDNMSVQERLKGFFNES 128

  Fly    66 VFDKFKELQLQSRLSKIVPIEGDVGLEHLGISPKDRQTLIDNVNVVFHSAATLDFFQSLKETTNI 130
            :|::.:| :....|:|:.||..|.....|.|...||..|...|.:||:..|::.|.:.|.:..:|
  Fly   129 IFNRMRE-ESPQLLAKVHPIRADYSAIDLDIDSADRAMLSSEVQIVFNVVASVKFNEKLSDAIDI 192

  Fly   131 NLRGTRRVVELCQQIKNLDALVHVSSAYVNAYLTKVEEKLYPAPEDPEKIIQLSETLNDDALKEL 195
            |:.||:::::|..::|:|.:.||:|:.|.|.....::|::|......|||:|:..|.:|:.|:::
  Fly   193 NVLGTKKILDLVMEMKHLKSFVHISTLYCNCNRKFIKEQVYENEIGYEKIMQIYRTFDDETLEKM 257

  Fly   196 EPKLLKDHPNTYTFTKHLAEHEVANVASKFPCGIVRPSMITAAWKEPIPGWTISKNGPQGFFMGA 260
            ...|:...|||||.||..||:.|.:.|...|.||.||.::.:.:|:|.||||.:..||.|....:
  Fly   258 RHCLIGQMPNTYTMTKKCAENLVNHRAFHMPAGIFRPPIVMSTYKDPFPGWTDNLYGPSGLCTWS 322

  Fly   261 SKGVLRRLPLDPSIIMDYIPIDVVVNGIITTGYYV----NSLQAKNGGRPADLQIFHLTSSTYKP 321
            ::|::|.:....|...:.:|.|.|||.:|.|.:.:    ...::|..|: ::|.:::..|
  Fly   323 ARGLVRCIYGKASCKANMVPADYVVNAMIATAWDIARRFKLRESKVDGK-SELPVYNYVS----- 381

  Fly   322 FRFELMTDKIN----SYLH------DYPLNSAVWYPNLRLVKSLWVFRLSAILFHFIPAIILDLV 376
                   |..|    .|:|      ..|.:.|:|..:..::.|..:....|...|.|||.||||:
  Fly   382 -------DANNITWGQYMHLSRKGFHEPFDKALWCFSYVIIPSKPLHCAIAFFLHNIPAYILDLI 439

  Fly   377 TKIGGGRPILVRLHKNVWNSLNTLEKFIFTEWHFDSKRLLALSKTLNIVDKKKFFIDIGELAWDE 441
            ..:.|.:.|..:.:..:...::.:..|...||.|..:.:..|::.|...::.....:|..:.|.|
  Fly   440 AMVTGQKRIYAKAYGKISRIIDMMAWFGLKEWKFAHRNIDELNELLPREERSVLQFNIATINWSE 504

  Fly   442 YFSNTILGVRQYLSKEPIKN--LEKARRKDKILLGLHVALQLSFWYGVFKLIVCL 494
            ||.:.:.|:|:|..|:...:  |::.|...:.:|.||..|:.:|.   ..||:|:
  Fly   505 YFRSYLSGIRRYFFKDSANDNKLQQRRTIYRRMLILHTLLKTTFG---LSLIMCM 556

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8306	NP_611140.3	PLN02996	6..456	CDD:215538	141/463 (30%)
		FAR-N_SDR_e	13..339	CDD:187547	108/339 (32%)
		FAR_C	364..454	CDD:176924	23/89 (26%)
CG34342	NP_001097509.3	PLN02996	70..519	CDD:215538	141/463 (30%)
		FAR-N_SDR_e	78..397	CDD:187547	108/333 (32%)
		Sterile	429..519	CDD:281068	24/89 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466805
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
	9	9.000