DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8306 and far1

DIOPT Version :9

Sequence 1:	NP_611140.3	Gene:	CG8306 / 36857	FlyBaseID:	FBgn0034142	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	XP_005174372.1	Gene:	far1 / 406829	ZFINID:	ZDB-GENE-040426-2908	Length:	518	Species:	Danio rerio

Alignment Length:	519	Identity:	170/519 - (32%)
Similarity:	275/519 - (52%)	Gaps:	29/519 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ITDFYAGRNVFITGATGFVGVTIVEKLLRDVPNVGTLYLLMRAKKGKSVQERLEELKKNSVFDKF 70
            |.::|.|:||.|||||||:|..::|||||..|.|...|:|:|.|.|::...|:.::....:||:.
Zfish     4 IPEYYVGKNVLITGATGFMGKVLLEKLLRSCPGVKAAYVLVRPKAGQAPDARIADMINCKLFDRL 68

  Fly    71 KELQLQSRLSKIVPIEGDVGLEHLGISPKDRQTLIDNVNVVFHSAATLDFFQSLKETTNINLRGT 135
            :|.| .....|||.|..|:...:|.:|.:|::||...:|||||.|||:.|.:.||:...:|:..|
Zfish    69 REDQ-PDFAGKIVAINSDLTQPNLDLSAEDQETLTGCINVVFHCAATIRFNEPLKDAMQLNVLAT 132

  Fly   136 RRVVELCQQIKNLDALVHVSSAYVNAYLTKVEEKLYPAPEDPEKIIQLSETLNDDALKELEPKLL 200
            :::|.|..::|:|:..:|||:||.|.....:||.:||.|.|..|:|...|.::|..:..:.|:||
Zfish   133 QKMVSLAHRMKHLEVFIHVSTAYANCDRELIEEVVYPPPVDYRKLIDTLEWMDDKLVSLMTPRLL 197

  Fly   201 KDHPNTYTFTKHLAEHEVANVASKFPCGIVRPSMITAAWKEPIPGWTISKNGPQGFFMGASKGVL 265
            .:.|||||:||.|||..|..........|:|||::.|:||||.|||..:.|||.|.|:.|.||:|
Zfish   198 GERPNTYTYTKALAEQLVQQECGNLNIAIIRPSIVGASWKEPFPGWIDNFNGPSGIFIAAGKGIL 262

  Fly   266 RRLPLDPSIIMDYIPIDVVVNGIITTGYYVNSLQAKNGGRPADLQIFHLTSSTYKPFRFELMTDK 330
            |.:....:.:.|.:|:|||:|..:...:|..|   :...||..|.:::.|:....||.:..:...
Zfish   263 RTMRASNNAVADLVPVDVVINTTLAAAWYSGS---QRHARPRSLLVYNCTTGGINPFHWGEVEYH 324

  Fly   331 INSYLHDYPLNSAVWYPNL-----RLVKSLWVFRLSAILFHFIPAIILDLVTKIGGGRP----IL 386
            :.|.....||..|...||:     .|:...|:     .:.|..||.:.||..::.|..|    .:
Zfish   325 VISTFKRNPLEQAFRRPNVNLTTNHLINQYWI-----AVSHKAPAFLYDLFLRMSGREPRMMKTI 384

  Fly   387 VRLHKNVWNSLNTLEKFIFTEWHFDSKRLLALSKTLNIVDKKKFFIDIGELAWDEYFSNTILGVR 451
            .||||    ::..||.|....|.:::..:..|...:...|||.|..|:.:|.|.||..|..:|.:
Zfish   385 TRLHK----AMMVLEYFTSHSWVWNTDNVTMLMNQMGAEDKKVFNFDVRQLHWAEYMENYCMGTK 445

  Fly   452 QYLSKEPIKNLEKARRKDKILLGLHVALQLSFWYGVFKLIVCLTGISTAKAALVLPVLYYLFGL 515
            :|:..|.:..|..||:.      |:....:.:.:... |:|.:..|..|::.:...:.|::..|
Zfish   446 KYVLNEELSGLPAARKH------LNKLRNIRYTFNTV-LVVLIWRIFIARSQMARNIWYFVVSL 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8306	NP_611140.3	PLN02996	6..456	CDD:215538	159/458 (35%)
		FAR-N_SDR_e	13..339	CDD:187547	121/325 (37%)
		FAR_C	364..454	CDD:176924	27/93 (29%)
far1	XP_005174372.1	FAR-N_SDR_e	11..333	CDD:187547	121/325 (37%)
far1	XP_005174372.1	Sterile	360..450	CDD:308580	28/93 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593281
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56516
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.960