DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8306 and CG10096

DIOPT Version :9

Sequence 1:	NP_611140.3	Gene:	CG8306 / 36857	FlyBaseID:	FBgn0034142	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_001027183.1	Gene:	CG10096 / 3772183	FlyBaseID:	FBgn0038032	Length:	502	Species:	Drosophila melanogaster

Alignment Length:	530	Identity:	169/530 - (31%)
Similarity:	277/530 - (52%)	Gaps:	50/530 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SSPITDFYAGRNVFITGATGFVGVTIVEKLLRDVPNVGTLYLLMRAKKGKSVQERLEELKKNSVF 67
            ::.:..||..:.||:||.:||:|...:.||| ....|..:|:|:|||:|:.::||.....|:.||
  Fly     2 ATDVQSFYKDKTVFLTGGSGFLGKVTIAKLL-CTTEVKRIYVLLRAKRGQEMRERCAAWDKDPVF 65

  Fly    68 DKFKELQLQSRLSKIVPIEGDVGLEHLGISPKDRQTLIDNVNVVFHSAATLDFFQSLKETTNINL 132
            ....:...:: |.::||..||.....||:|..|||.|||.|.:|.|:|||:.|.:.|.....:|.
  Fly    66 GNLMKTNPEA-LKRVVPCGGDCQEPDLGLSNSDRQVLIDEVQIVIHTAATVRFVEPLHIALAVNT 129

  Fly   133 RGTRRVVELCQQIKNLDALVHVSSAYVNAYLTKVEEKLYP----APEDPEKIIQLSETLNDDALK 193
            |.||.:::|.:::.:|::.||||:||.|..:..|.|:.||    .|  .|||::|.|:::.:.|.
  Fly   130 RATRLMIQLAKEMSHLESFVHVSTAYSNCVVEHVSERFYPEHLTCP--AEKILELLESISPELLD 192

  Fly   194 ELEPKLLKDHPNTYTFTKHLAEHEVANVASKFPCGIVRPSMITAAWKEPIPGWTISKNGPQGFFM 258
            ::.|.|:..:|||||:||.|.|..:...|...|..|.||.:|.|::|||:|||..:..||.....
  Fly   193 KMAPALMGKYPNTYTYTKALTEQVIQKEAKDLPLSIFRPGVIIASYKEPMPGWIDNLYGPIAVLY 257

  Fly   259 GASKGVLRRLPLDPSIIMDYIPIDVVVNGIITTGYYVNSLQAKNGGRPADLQ------IFHLTSS 317
            ||:.|:|....|:.......:|:|..||.::|..:        |..|...::      |::.|.:
  Fly   258 GAAFGILHITLLNLKAQAGIVPVDYCVNMVLTCAW--------NTARDTSIKLSPEPPIYNFTPN 314

  Fly   318 -----TYKPFRFELMTDKINSYLHDYPLNSAVWYPNLRLVKSLWVFRLSAILFHFIPAIILDLVT 377
                 |:..||     ||.....:.|||...:|.|.|......|:||.:||.:|.:|...:||..
  Fly   315 NDNLITWGGFR-----DKAARLRYTYPLTKMMWLPFLHCTTIPWLFRFTAIFYHLLPGYAIDLAL 374

  Fly   378 KIGGGRPILVRLHKNVWNSLNTLEKFIFTEWHFDSKRLLALSKTLNIVDKKKFFIDIGELAWDEY 442
            ::.|.:|.:::|:..:..:::.|..|:.|.|.||:.....|...:::.|:|.:..::..:.||:|
  Fly   375 RLWGKKPRMIKLYDKIHKNIDILAPFVITSWSFDTVNTRKLWAKMSVEDQKLYDFNMSSVDWDDY 439

  Fly   443 FSNTILGVRQYLSK-EPIKN-LEKARRKDKILLGLHVALQLSFWYGVFKLIVCLTGISTAKAALV 505
            |...:.|||.||:| ||.:. :|:.|:..|....||..||.:...|               |||:
  Fly   440 FLQALAGVRIYLAKEEPGQEVVERGRKIYKRFEFLHRLLQFTLCGG---------------AALI 489

  Fly   506 L-PVLYYLFG 514
            | .:|..|.|
  Fly   490 LWSILKRLLG 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8306	NP_611140.3	PLN02996	6..456	CDD:215538	151/464 (33%)
		FAR-N_SDR_e	13..339	CDD:187547	113/340 (33%)
		FAR_C	364..454	CDD:176924	23/89 (26%)
CG10096	NP_001027183.1	PLN02996	1..441	CDD:215538	145/455 (32%)
		FAR-N_SDR_e	12..330	CDD:187547	113/334 (34%)
		Sterile	363..453	CDD:281068	25/89 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466801
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
	9	8.890