DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8306 and far1

DIOPT Version :9

Sequence 1:	NP_611140.3	Gene:	CG8306 / 36857	FlyBaseID:	FBgn0034142	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	XP_017948360.1	Gene:	far1 / 100038270	XenbaseID:	XB-GENE-973776	Length:	518	Species:	Xenopus tropicalis

Alignment Length:	518	Identity:	178/518 - (34%)
Similarity:	289/518 - (55%)	Gaps:	27/518 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ITDFYAGRNVFITGATGFVGVTIVEKLLRDVPNVGTLYLLMRAKKGKSVQERLEELKKNSVFDKF 70
            |.:||.|:||.|||||||:|..::|||||..|||..:|:|:|.|..:..:||:.|:....:||:.
Frog     4 IPEFYRGKNVLITGATGFMGKVLLEKLLRSCPNVKAVYVLVRPKASQKPRERVAEMMSCKLFDRL 68

  Fly    71 KELQLQSRLSKIVPIEGDVGLEHLGISPKDRQTLIDNVNVVFHSAATLDFFQSLKETTNINLRGT 135
            ::.|.:. ..|::.|..::....|.:|.:|:..|||.:::|||.|||:.|.:||::...:|:..|
Frog    69 RDEQPEC-AQKVIAISSELTQPELDLSKEDQDMLIDCIDIVFHCAATVRFNESLRDAMQLNVIAT 132

  Fly   136 RRVVELCQQIKNLDALVHVSSAYVNAYLTKVEEKLYPAPEDPEKIIQLSETLNDDALKELEPKLL 200
            |:::.|.|:||.|:..:|||:||.|....::||.:||.|.||:|:|:..|.::|..:.::.|||:
Frog   133 RQLLYLAQKIKKLEVFIHVSTAYANCNRKQIEEMVYPPPVDPKKLIESLEWMDDGLVNDITPKLI 197

  Fly   201 KDHPNTYTFTKHLAEHEVANVASKFPCGIVRPSMITAAWKEPIPGWTISKNGPQGFFMGASKGVL 265
            .|.|||||:||.|||:.|....||....|||||::.|:||||.|||..:.|||.|.|:.|.||:|
Frog   198 GDRPNTYTYTKALAEYVVQQEGSKLNIAIVRPSIVGASWKEPFPGWIDNFNGPSGLFIAAGKGIL 262

  Fly   266 RRLPLDPSIIMDYIPIDVVVNGIITTGYY--VNSLQAKNGGRPADLQIFHLTSSTYKPFRFELMT 328
            |.:....:.:.|.||:|||||..:...:|  ||..     .||.::.:::.|:....||.:..:.
Frog   263 RTMRASNNAVADLIPVDVVVNTTLAAAWYSGVNRY-----SRPRNILVYNCTTGGTNPFHWGEVE 322

  Fly   329 DKINSYLHDYPLNSAVWYPNLRLVKSLWVFRLSAILFHFIPAIILDLVTKIGGGRP----ILVRL 389
            ..:.|.....||..|...||:.|..:..::.....:.|..||.:.|:..:|.|..|    .:.||
Frog   323 YHVISTFKRNPLEQAFRRPNVNLTSNHLLYHYWIAVSHKAPAFLYDVYLRITGRSPRMMKTITRL 387

  Fly   390 HKNVWNSLNTLEKFIFTEWHFDSKRLLALSKTLNIVDKKKFFIDIGELAWDEYFSNTILGVRQYL 454
            ||    ::..||.|....|.::::....|...|:..|||.|..|:.:|.|.||..|..:|.::|:
Frog   388 HK----AMMLLEYFTSNSWVWNNENTNMLMSQLSPDDKKAFNFDVRQLHWAEYMENYCMGTKKYV 448

  Fly   455 SKEPIKNLEKARRKDKILLGLHVALQLSFWYGVFK--LIVCLTGISTAKAALVLPVLYYLFGL 515
            ..|.:..|..||:        |:....:..|| |.  |:|.:..:..|::.:...:.|::..:
Frog   449 LNEEMSGLPAARK--------HLNKLRNIRYG-FNTILVVLIWRVFIARSQMARNIWYFVVSM 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8306	NP_611140.3	PLN02996	6..456	CDD:215538	166/455 (36%)
		FAR-N_SDR_e	13..339	CDD:187547	127/327 (39%)
		FAR_C	364..454	CDD:176924	28/93 (30%)
far1	XP_017948360.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56516
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.030