DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8306 and si:dkey-97m3.1

DIOPT Version :9

Sequence 1:	NP_611140.3	Gene:	CG8306 / 36857	FlyBaseID:	FBgn0034142	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_001076558.1	Gene:	si:dkey-97m3.1 / 100034578	ZFINID:	ZDB-GENE-060503-367	Length:	515	Species:	Danio rerio

Alignment Length:	519	Identity:	170/519 - (32%)
Similarity:	292/519 - (56%)	Gaps:	27/519 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ITDFYAGRNVFITGATGFVGVTIVEKLLRDVPNVGTLYLLMRAKKGKSVQERLEELKKNSVFDKF 70
            |:::|||:||.|||||||:|..:||||||..|:|..||:|:|.|.|:|:.||::::.|..:||:.
Zfish     4 ISEWYAGKNVLITGATGFMGKVLVEKLLRSCPDVNALYILVRPKAGQSMSERVQDMMKCKLFDRV 68

  Fly    71 KELQLQSRLSKIVPIEGDVGLEHLGISPKDRQTLIDNVNVVFHSAATLDFFQSLKETTNINLRGT 135
            :|...:.. .||:.|..::....|.||.:|.:||...|::|||.|||:.|.:.||....:|:..|
Zfish    69 REDNPEFH-QKIIAISSELMQPGLAISAQDVETLTSRVHIVFHCAATIRFDEPLKHALQLNVMAT 132

  Fly   136 RRVVELCQQIKNLDALVHVSSAYVNAYLTKVEEKLYPAPEDPEKIIQLSETLNDDALKELEPKLL 200
            ::::.|.||::.|.|.:|:|:||.|.....::|.:||.|.:|.|:|...|.:::..::::.|:|:
Zfish   133 QQLLSLAQQMQQLQAFIHISTAYANCNRRHIDELIYPPPVEPRKLIDSLEWMDESIIRDITPRLI 197

  Fly   201 KDHPNTYTFTKHLAEHEVANVASKFPCGIVRPSMITAAWKEPIPGWTISKNGPQGFFMGASKGVL 265
            .|.|||||:||.|||..|...::|...||||||::.|:|:||.|||..:.|||.|.|:.|.||:|
Zfish   198 GDWPNTYTYTKALAECVVQQESAKLNVGIVRPSIVGASWQEPFPGWIDNFNGPSGVFIAAGKGIL 262

  Fly   266 RRLPLDPSIIMDYIPIDVVVNGIITTGYYVNSLQAKNGGRPADLQIFHLTSSTYKPFRFELMTDK 330
            |.:......:.|.||:|||:|..:..|:|.    |.|  :|....:::.|:....||.:..:...
Zfish   263 RTMRASNDAVADLIPVDVVINLTLAAGWYT----AVN--KPKTALVYNCTTGGINPFHWGEIEHH 321

  Fly   331 INSYLHDYPLNSAVWYPNLRLVKSLWVFRLSAILFHFIPAIILDLVTKIGGGRPILVRLHKNVWN 395
            :.|.....||..|...||..:..:..:::...::.|.:||::.||:.::.|.:|.::|:...:..
Zfish   322 VMSTFKRNPLEQAFRRPNANITSNYLIYQYWILVSHKVPALLYDLLLRLSGHKPQMMRIFNRLHK 386

  Fly   396 SLNTLEKFIFTEWHFDSKRLLALSKTLNIVDKKKFFIDIGELAWDEYFSNTILGVRQYLSKEPIK 460
            ::..||.|...:|.::|..:..|...|:..|:|.|..|:.:|.|.||..|..:|.::|:..|.:.
Zfish   387 AIGLLEYFSSQDWEWNSDNMNMLMAQLSTDDRKIFNFDVRQLNWPEYIENYCIGTKKYVLNEDMS 451

  Fly   461 NLEKARRKDKILLGLHVA------------------LQLSFWYGVFKLIVCLTGISTAKAALVL 506
            ::..||:..:.|..:...                  :..:.||  |.:.:|...:|..:|:..|
Zfish   452 DIPAARQHLRKLRNIRYTFNTVLLVFIWRVFIARSQMARNIWY--FVVSLCFKFLSYFRASSTL 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8306	NP_611140.3	PLN02996	6..456	CDD:215538	159/449 (35%)
		FAR-N_SDR_e	13..339	CDD:187547	124/325 (38%)
		FAR_C	364..454	CDD:176924	25/89 (28%)
si:dkey-97m3.1	NP_001076558.1	PLN02996	2..446	CDD:215538	159/448 (35%)
		FAR-N_SDR_e	11..330	CDD:187547	124/325 (38%)
		Sterile	357..447	CDD:281068	26/89 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593298
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3320
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56516
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.760