Protein Alignment Cdk4 and PHO85

DIOPT Version :9

• Sequence 1: NP_001286493.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_015294.1
• Gene: PHO85 / 856076
• SGDID: S000005952
• Length: 305
• Species: Saccharomyces cerevisiae
• Alignment Length: 318
• Identity: 119/318 - (37%)
• Similarity: 188/318 - (59%)
• Gaps: 34/318 - (10%)

  Fly    12 MSQAKKFGDGDPFNYQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLREISL 76
            ||.:.:|        ::|..:|.|.|.|||:..:..||..||||:|::. :|.|.|.:.:|||||
Yeast     1 MSSSSQF--------KQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLD-SEEGTPSTAIREISL 56

  Fly    77 LKQLNASNHANIVKLYEVCQFLERDGQLLILLVFEHVEQDLSDLID-----RLPKSGMSPPTIQR 136
            :|:|   .|.|||:||:|   :..:.:|  .||||.::.||...:|     ..|: |:....::.
Yeast    57 MKEL---KHENIVRLYDV---IHTENKL--TLVFEFMDNDLKKYMDSRTVGNTPR-GLELNLVKY 112

  Fly   137 LSRELLTGVDFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLAKTYGSEMK-LTSVVVTLWYRAP 200
            ...:||.|:.|.|.::|:||||||||||::.:|.||:.|||||:.:|..:. .:|.|||||||||
Yeast   113 FQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAP 177

  Fly   201 EVLL-AQPYNSTVDIWSAACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWPQTISVALE 264
            :||: ::.|::::||||..||:.||...:.|||||:::.||..||::.|.|.|..|| :::...:
Yeast   178 DVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTPNESLWP-SVTKLPK 241

  Fly   265 HFPQRHPKRPKD----FCPHLCKYAD----DLLNKMLSYDLHLRPSALACLEHDYFQQ 314
            :.|....:.|:|    ..||..:..|    |.|:.:|..:..:|.||...|.|.:|.:
Yeast   242 YNPNIQQRPPRDLRQVLQPHTKEPLDGNLMDFLHGLLQLNPDMRLSAKQALHHPWFAE 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_001286493.1	STKc_CDK4_6_like	26..312	CDD:270831	115/300 (38%)
		S_TKc	26..312	CDD:214567	115/300 (38%)
PHO85	NP_015294.1	PKc_like	6..297	CDD:419665	116/309 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0594
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810