Protein Alignment Cdk4 and CTK1

DIOPT Version :10

• Sequence 1: NP_477196.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_012783.1
• Gene: CTK1 / 853718
• SGDID: S000001622
• Length: 528
• Species: Saccharomyces cerevisiae
• Alignment Length: 307
• Identity: 109/307 - (35%)
• Similarity: 175/307 - (57%)
• Gaps: 32/307 - (10%)

  Fly    26 YQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLREISLLKQLNASNHANIVK 90
            |..:..:|||.||.||:|::..|..:|||||:|:.....|.|::::|||.||:..   :|.|:..
Yeast   183 YLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSF---DHPNVST 244

  Fly    91 LYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKS-GMSPPTIQRLSRELLTGVDFLHSHRII 154
            :.|:..    :.|..:.::||:.:.|||.|:  |.|. .:|....:.|.::||.|:::||.::|:
Yeast   245 IKEIMV----ESQKTVYMIFEYADNDLSGLL--LNKEVQISHSQCKHLFKQLLLGMEYLHDNKIL 303

  Fly   155 HRDLKPQNLLVSSQGHLKIADFGLAKTYGSEMKLTSVVVTLWYRAPEVLLAQP-YNSTVDIWSAA 218
            |||:|..|:|:.:||:|||.|||||:...|....|:.|:|||||.||:||... |.:.||:|...
Yeast   304 HRDVKGSNILIDNQGNLKITDFGLARKMNSRADYTNRVITLWYRPPELLLGTTNYGTEVDMWGCG 368

  Fly   219 CIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQW-------------PQTISVALEHFPQRH 270
            |::.|:||:.|:|.|::|..|::.||::.|.||...|             ||..:..:.:|.::.
Yeast   369 CLLVELFNKTAIFQGSNELEQIESIFKIMGTPTINSWPTLYDMPWFFMIMPQQTTKYVNNFSEKF 433

  Fly   271 PK-RPKDFCPHLCKYADDLLNKMLSYDLHLRPSALACLEHDYFQQEP 316
            .. .|...|..|.      :| :|.||...|.||...|:.|||::||
Yeast   434 KSVLPSSKCLQLA------IN-LLCYDQTKRFSATEALQSDYFKEEP 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_477196.1	STKc_CDK4_6_like	26..312	CDD:270831	105/301 (35%)
CTK1	NP_012783.1	STKc_CDK9_like	183..469	CDD:270832	105/301 (35%)