Protein Alignment Cdk4 and KDX1

DIOPT Version :10

• Sequence 1: NP_477196.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_012761.1
• Gene: KDX1 / 853696
• SGDID: S000001644
• Length: 433
• Species: Saccharomyces cerevisiae
• Alignment Length: 298
• Identity: 92/298 - (30%)
• Similarity: 148/298 - (49%)
• Gaps: 27/298 - (9%)

  Fly    32 IGEGAYGTV----YRARDVITGNIVALKKVRISLNENGVPMS---TLREISLLKQLNASNHANIV 89
            ||.|::..:    |...:..|.  ||::|:.   |..|..:|   ||||:.||:.|.  .|.|||
Yeast    29 IGRGSHSLICSSTYTESNEETH--VAIRKIP---NAFGNKLSCKRTLRELKLLRHLR--GHPNIV 86

  Fly    90 KLYEVCQFLERDGQLLILLVFEH-VEQDLSDLIDRLPKSGMSPPTIQRLSRELLTGVDFLHSHRI 153
            .|::.......:|.|..:.::|. :|.|||.:|  ..:..:.....|....::|..:.::||..:
Yeast    87 WLFDTDIVFYPNGALNGVYLYEELMECDLSQII--RSEQRLEDAHFQSFIYQILCALKYIHSANV 149

  Fly   154 IHRDLKPQNLLVSSQGHLKIADFGLAKTYGSEMK-----LTSVVVTLWYRAPEVLL-AQPYNSTV 212
            :|.||||:||||:|...|||.:|||:.:|....|     :...:.::||:|||:|| .|.....|
Yeast   150 LHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAV 214

  Fly   213 DIWSAACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWPQTISVALEHFPQRHPKRP--- 274
            ||||..||:.|:..|:.:|.|....:.|:.|.::.|.|.|:...:..|..:.::..:....|
Yeast   215 DIWSTGCILAELLGRKPMFEGKDYVDHLNHILQILGTPPEETLQEIASQKVYNYIFQFGNIPGRS 279

  Fly   275 -KDFCPHLCKYADDLLNKMLSYDLHLRPSALACLEHDY 311
             :...|.....|.:||.|||.:|...|.:....|||.|
Yeast   280 FESILPGANPEALELLKKMLEFDPKKRITVEDALEHPY 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_477196.1	STKc_CDK4_6_like	26..312	CDD:270831	92/298 (31%)
KDX1	NP_012761.1	STKc_MPK1	22..355	CDD:173750	92/298 (31%)