Protein Alignment Cdk4 and CAK4

DIOPT Version :10

• Sequence 1: NP_477196.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_176847.1
• Gene: CAK4 / 842993
• AraportID: AT1G66750
• Length: 348
• Species: Arabidopsis thaliana
• Alignment Length: 306
• Identity: 121/306 - (39%)
• Similarity: 168/306 - (54%)
• Gaps: 17/306 - (5%)

  Fly    17 KFGDGDPFN-YQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLREISLLKQL 80
            |.||..|.: |....|:|||.||.||:|.|..||..||:||:|:...:.||..:.||||.|||:|
plant     3 KSGDNQPVDRYLRRQILGEGTYGVVYKATDTKTGKTVAVKKIRLGNQKEGVNFTALREIKLLKEL 67

  Fly    81 NASNHANIVKLYEVCQFLERDGQLLILLVFEHVEQDLSDLI-DRLPKSGMSPPTIQRLSRELLTG 144
               ||.:||:|.:.   ...||.|  .||||:::.||..:| ||  ...:||..|:......|.|
plant    68 ---NHPHIVELIDA---FPHDGSL--HLVFEYMQTDLEAVIRDR--NIFLSPGDIKSYMLMTLKG 122

  Fly   145 VDFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLAKTYGS-EMKLTSVVVTLWYRAPEVLL-AQP 207
            :.:.|...::|||:||.|||:...|.||:||||||:.:|| ..:.|..|...||||||:|. ::.
plant   123 LAYCHKKWVLHRDMKPNNLLIGENGLLKLADFGLARLFGSPNRRFTHQVFATWYRAPELLFGSRQ 187

  Fly   208 YNSTVDIWSAACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWPQTISVALEHFPQRHPK 272
            |.:.||:|:|.||..|:..||...||::|.:||.:||:..|.|...||...|.:. ::....:..
plant   188 YGAGVDVWAAGCIFAELLLRRPFLPGSTEIDQLGKIFQAFGTPVPSQWSDMIYLP-DYMEFSYTP 251

  Fly   273 RP--KDFCPHLCKYADDLLNKMLSYDLHLRPSALACLEHDYFQQEP 316
            .|  :...|.....|.|||.||..||...|.:....|:|.||...|
plant   252 APPLRTIFPMASDDALDLLAKMFIYDPRQRITIQQALDHRYFSSSP 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_477196.1	STKc_CDK4_6_like	26..312	CDD:270831	114/290 (39%)
CAK4	NP_176847.1	STKc_CDK7	12..305	CDD:270833	117/297 (39%)