Protein Alignment Cdk4 and CDKE;1

DIOPT Version :10

• Sequence 1: NP_477196.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_201166.1
• Gene: CDKE;1 / 836481
• AraportID: AT5G63610
• Length: 470
• Species: Arabidopsis thaliana
• Alignment Length: 355
• Identity: 129/355 - (36%)
• Similarity: 188/355 - (52%)
• Gaps: 74/355 - (20%)

  Fly    19 GDGD-------------PFNYQELNI---IGEGAYGTVYRAR-DVITGNIVALKKVRISLNENGV 66
            |||.             |...|:.|:   ||||.||.|:.|| .......:|:||.:.|.:.:||
plant     2 GDGSSSRSNSSNSTSEKPEWLQQYNLVGKIGEGTYGLVFLARTKTPPKRPIAIKKFKQSKDGDGV 66

  Fly    67 PMSTLREISLLKQLNASNHANIVKLYEV-CQFLERDGQLLILLVFEHVEQDLSDLI----DRLPK 126
            ..:.:|||.||:::   :|.|:|||..| ..|.:    :.:.|.|::.|.||.::|    |::..
plant    67 SPTAIREIMLLREI---SHENVVKLVNVHINFAD----MSLYLAFDYAEYDLYEIIRHHRDKVGH 124

  Fly   127 SGMSPPTIQRLSRELLTGVDFLHSHRIIHRDLKPQNLLV----SSQGHLKIADFGLAKTYGSEMK 187
            | ::..|::.|..:||.|:::|||:.||||||||.|:||    ...|.:||||||||:.|.:.:|
plant   125 S-LNTYTVKSLLWQLLNGLNYLHSNWIIHRDLKPSNILVMGDAEEHGIVKIADFGLARIYQAPLK 188

  Fly   188 LTS---VVVTLWYRAPEVLL-AQPYNSTVDIWSAACIIFEMFNRRALFPGTSEK--------NQL 240
            ..|   ||||:||||||:|| ::.|.|.||:|:..||..|:...:.||.|...|        :||
plant   189 PLSDNGVVVTIWYRAPELLLGSKHYTSAVDMWAVGCIFAELLTLKPLFQGAEAKSSQNPFQLDQL 253

  Fly   241 DRIFELTGRPTEQQWPQTI------------------SVALEHFPQRHPKRPKDFCPHLCKYADD 287
            |:||::.|.||..:||..:                  ||.|.:....:.|.|          |.|
plant   254 DKIFKILGHPTMDKWPTLVNLPHWQNDVQHIQAHKYDSVGLHNVVHLNQKSP----------AYD 308

  Fly   288 LLNKMLSYDLHLRPSALACLEHDYFQQEPL 317
            ||:|||.||...|.:|...|||:||:.:||
plant   309 LLSKMLEYDPLKRITASQALEHEYFRMDPL 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_477196.1	STKc_CDK4_6_like	26..312	CDD:270831	121/328 (37%)
CDKE;1	NP_201166.1	STKc_CDK8_like	24..333	CDD:270834	120/326 (37%)