Protein Alignment Cdk4 and MHK

DIOPT Version :10

• Sequence 1: NP_477196.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_001031622.1
• Gene: MHK / 826915
• AraportID: AT4G13020
• Length: 444
• Species: Arabidopsis thaliana
• Alignment Length: 296
• Identity: 105/296 - (35%)
• Similarity: 164/296 - (55%)
• Gaps: 25/296 - (8%)

  Fly    26 YQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLN--ENGVPMSTLREISLLKQLNASNHANI 88
            |:.|..:|:|..|:||:|.::.|..:||:||::....  |..|   .|||:..|::|   ||.:|
plant    12 YKILEELGDGTCGSVYKAVNLETYEVVAVKKMKRKFYYWEECV---NLREVKALRKL---NHPHI 70

  Fly    89 VKLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSPPTIQRLSRELLTGVDFLHSHRI 153
            :||.|:.:  |.:.   :..:||.::.:|..::....:. .|...|:....::|.|:..:|.:..
plant    71 IKLKEIVR--EHNE---LFFIFECMDHNLYHIMKERERP-FSEGEIRSFMSQMLQGLAHMHKNGY 129

  Fly   154 IHRDLKPQNLLVSSQGHLKIADFGLAKTYGSEMKLTSVVVTLWYRAPEVLL-AQPYNSTVDIWSA 217
            .||||||:||||:: ..|||||||||:...|....|..|.|.||||||||| :..|...||:|:.
plant   130 FHRDLKPENLLVTN-NILKIADFGLAREVASMPPYTEYVSTRWYRAPEVLLQSSLYTPAVDMWAV 193

  Fly   218 ACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWPQTISV----ALEH--FPQRHPKRPKD 276
            ..|:.|::....||||.||.:||.:|..:.|:|....:|:..|:    ::.|  |||   .|..|
plant   194 GAILAELYALTPLFPGESEIDQLYKICCVLGKPDWTTFPEAKSISRIMSISHTEFPQ---TRIAD 255

  Fly   277 FCPHLCKYADDLLNKMLSYDLHLRPSALACLEHDYF 312
            ..|:....|.||:|::.|:|...||:|...|.|.:|
plant   256 LLPNAAPEAIDLINRLCSWDPLKRPTADEALNHPFF 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_477196.1	STKc_CDK4_6_like	26..312	CDD:270831	104/294 (35%)
MHK	NP_001031622.1	STKc_MAK_like	12..291	CDD:270824	104/294 (35%)