DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cdk4 and CDC2

DIOPT Version :9

Sequence 1:NP_001286493.1 Gene:Cdk4 / 36854 FlyBaseID:FBgn0016131 Length:317 Species:Drosophila melanogaster
Sequence 2:NP_566911.1 Gene:CDC2 / 824036 AraportID:AT3G48750 Length:294 Species:Arabidopsis thaliana


Alignment Length:293 Identity:129/293 - (44%)
Similarity:182/293 - (62%) Gaps:13/293 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly    26 YQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLREISLLKQLNASNHANIVK 90
            |:::..||||.||.||:|||.:|...:||||:|:...:.|||.:.:|||||||::   .|:||||
plant     4 YEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEM---QHSNIVK 65

  Fly    91 LYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSPPTIQRLSRELLTGVDFLHSHRIIH 155
            |.:|....:|     :.||||:::.||...:|..|........|:....::|.|:.:.||||::|
plant    66 LQDVVHSEKR-----LYLVFEYLDLDLKKHMDSTPDFSKDLHMIKTYLYQILRGIAYCHSHRVLH 125

  Fly   156 RDLKPQNLLVSSQ-GHLKIADFGLAKTYGSEMK-LTSVVVTLWYRAPEVLL-AQPYNSTVDIWSA 217
            |||||||||:..: ..||:||||||:.:|..:: .|..||||||||||:|| :..|::.|||||.
plant   126 RDLKPQNLLIDRRTNSLKLADFGLARAFGIPVRTFTHEVVTLWYRAPEILLGSHHYSTPVDIWSV 190

  Fly   218 ACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWPQTISVA--LEHFPQRHPKRPKDFCPH 280
            .||..||.:::.||||.||.:||.:||.:.|.|.|..|....|:.  ...||:..|...:.|.|:
plant   191 GCIFAEMISQKPLFPGDSEIDQLFKIFRIMGTPYEDTWRGVTSLPDYKSAFPKWKPTDLETFVPN 255

  Fly   281 LCKYADDLLNKMLSYDLHLRPSALACLEHDYFQ 313
            |.....|||:|||..|...|.:|.|.|||:||:
plant   256 LDPDGVDLLSKMLLMDPTKRINARAALEHEYFK 288

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cdk4NP_001286493.1 STKc_CDK4_6_like 26..312 CDD:270831 127/290 (44%)
S_TKc 26..312 CDD:214567 127/290 (44%)
CDC2NP_566911.1 PLN00009 1..294 CDD:177649 129/293 (44%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0594
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24056
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
43.910

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