Protein Alignment Cdk4 and cdk1

DIOPT Version :10

• Sequence 1: NP_477196.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_997729.1
• Gene: cdk1 / 80973
• ZFINID: ZDB-GENE-010320-1
• Length: 302
• Species: Danio rerio
• Alignment Length: 296
• Identity: 128/296 - (43%)
• Similarity: 177/296 - (59%)
• Gaps: 19/296 - (6%)

  Fly    25 NYQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLREISLLKQLNASNHANIV 89
            :|.::..||||.||.||:.|:..||.:||:||:|:...|.|||.:.:|||||||:|   .|.|:|
Zfish     3 DYLKIEKIGEGTYGVVYKGRNKTTGQVVAMKKIRLESEEEGVPSTAVREISLLKEL---QHPNVV 64

  Fly    90 KLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSG--MSPPTIQRLSRELLTGVDFLHSHR 152
            :|.:|   |.::.:|  .||||.:..||...:|.:| ||  |.|..::....::|.|:.|.|..|
Zfish    65 RLLDV---LMQESKL--YLVFEFLSMDLKKYLDSIP-SGEFMDPMLVKSYLYQILEGILFCHCRR 123

  Fly   153 IIHRDLKPQNLLVSSQGHLKIADFGLAKTYGSEMKL-TSVVVTLWYRAPEVLL-AQPYNSTVDIW 215
            ::||||||||||:.::|.:|:||||||:.:|..::: |..||||||||||||| |..|::.||:|
Zfish   124 VLHRDLKPQNLLIDNKGVIKLADFGLARAFGVPVRVYTHEVVTLWYRAPEVLLGASRYSTPVDLW 188

  Fly   216 SAACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWPQTISVALEHFPQRHPKRPKDFCPH 280
            |...|..|:..::.||.|.||.:||.|||...|.|..:.||...|  |..:....||.......:
Zfish   189 SIGTIFAELATKKPLFHGDSEIDQLFRIFRTLGTPNNEVWPDVES--LPDYKNTFPKWKSGNLAN 251

  Fly   281 LCKYAD----DLLNKMLSYDLHLRPSALACLEHDYF 312
            ..|..|    |||.|||.||...|.||...:.|.||
Zfish   252 TVKNLDKNGIDLLMKMLIYDPPKRISARQAMTHPYF 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_477196.1	STKc_CDK4_6_like	26..312	CDD:270831	126/293 (43%)
cdk1	NP_997729.1	STKc_CDK1_euk	3..287	CDD:270845	126/294 (43%)