Protein Alignment Cdk4 and cdk17

DIOPT Version :9

• Sequence 1: NP_001286493.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_001188286.1
• Gene: cdk17 / 798487
• ZFINID: ZDB-GENE-041210-15
• Length: 526
• Species: Danio rerio
• Alignment Length: 317
• Identity: 121/317 - (38%)
• Similarity: 184/317 - (58%)
• Gaps: 27/317 - (8%)

  Fly     8 KRQKMSQAKKFGDGDPFNYQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLR 72
            :|.:.:...:.|.|....|.:|:.:|||.|.||::.|..:|.|:||||::|:. :|.|.|.:.:|
Zfish   177 RRSRRASLSEIGFGKLETYIKLDKLGEGTYATVFKGRSKLTDNLVALKEIRLE-HEEGAPCTAIR 240

  Fly    73 EISLLKQLNASNHANIVKLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSPPTIQRL 137
            |:||||.|   .|||||.|:::   :..|..|  .||||::::||...:|..... ||...::..
Zfish   241 EVSLLKDL---KHANIVTLHDI---VHTDKSL--TLVFEYLDKDLKQYMDDCGNI-MSMHNVKIF 296

  Fly   138 SRELLTGVDFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLA-------KTYGSEMKLTSVVVTL 195
            ..::|.|:.:.|..:::||||||||||::.:|.||:||||||       |||.:|      ||||
Zfish   297 LFQILRGLAYCHRRKVLHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNE------VVTL 355

  Fly   196 WYRAPEVLL-AQPYNSTVDIWSAACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWPQTI 259
            |||.|:||| :..|::.:|:|...||.:||...|.||||::.:::|..||.|.|.|||..||...
Zfish   356 WYRPPDVLLGSSEYSTQIDMWGVGCIFYEMAAGRPLFPGSTVEDELHLIFRLLGTPTEDNWPGIS 420

  Fly   260 SV---ALEHFPQRHPKRPKDFCPHLCKYADDLLNKMLSYDLHLRPSALACLEHDYFQ 313
            |:   ...:||:..|:...:..|.|.....:||...|.|:...|.||...::|.||:
Zfish   421 SIEEFKSYNFPKYKPQPFINHAPRLDTEGIELLLSFLRYESKKRISADESMKHSYFK 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_001286493.1	STKc_CDK4_6_like	26..312	CDD:270831	116/296 (39%)
		S_TKc	26..312	CDD:214567	116/296 (39%)
cdk17	NP_001188286.1	STKc_PCTAIRE2	188..496	CDD:143377	120/306 (39%)
		PLN00009	192..481	CDD:177649	118/302 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0594
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810