Protein Alignment Cdk4 and cdk15

DIOPT Version :9

• Sequence 1: NP_001286493.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: XP_005165792.1
• Gene: cdk15 / 791619
• ZFINID: ZDB-GENE-060421-7193
• Length: 461
• Species: Danio rerio
• Alignment Length: 350
• Identity: 122/350 - (34%)
• Similarity: 178/350 - (50%)
• Gaps: 60/350 - (17%)

  Fly     6 QLKRQKMSQAKKFGD-------------------GDPFNYQELNIIGEGAYGTVYRARDVITGNI 51
            |::|.::.:.:...|                   |:..:|..|..:|||.|.|||:....|.|::
Zfish    88 QVRRLRVQRGRSNSDPMGGKSFQQEFQWKTGLQFGNATSYLNLEKLGEGTYATVYKGISRINGHL 152

  Fly    52 VALKKVRISLNENGVPMSTLREISLLKQLNASNHANIVKLYEVCQFLERDGQLLILLVFEHVEQD 116
            ||||.:.:. .|.|:|.:.:||.||||.|   .|||||.|:::....|.     :..|||:|:.|
Zfish   153 VALKVIHMK-TEEGIPFTAIREASLLKGL---KHANIVLLHDIIHTRES-----LTFVFEYVQTD 208

  Fly   117 LSDLIDRLPKSGMSPPTIQRLSRELLTGVDFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLAK- 180
            |:..:.:.| .|:....|:....:||.|:.::|..||:||||||||||:|..|.||:||||||:
Zfish   209 LAQYMIQHP-GGLHSYNIRLFMFQLLRGLSYIHGRRILHRDLKPQNLLISYLGELKLADFGLARS 272

  Fly   181 ------TYGSEMKLTSVVVTLWYRAPEVLL-AQPYNSTVDIWSAACIIFEMFNRRALFPGTSEK- 237
                  ||.:|      |||||||.|:||: :..|::.:|||.|.||..||......|||.::.
Zfish   273 KSIPCQTYSAE------VVTLWYRPPDVLMGSTDYSTALDIWGAGCIFIEMLQGSPAFPGVADVF 331

  Fly   238 NQLDRIFELTGRPTEQQWPQTISVALEHFPQRHPK-----RPKDF------CPHLCKYADDLLNK 291
            .||.:|:.:.|.|||:.||     .:...|...|:     :|:.|      ...|....:||..:
Zfish   332 EQLLKIWTVIGVPTEEIWP-----GVSDLPNYKPEWFLPCKPQQFRDVWKRLSQLPYKTEDLAQQ 391

  Fly   292 MLSYDLHLRPSALACLEHDYFQQEP 316
            ||..:...|.||...|.|.||...|
Zfish   392 MLMMNPKDRISAQDALLHPYFNTLP 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_001286493.1	STKc_CDK4_6_like	26..312	CDD:270831	115/305 (38%)
		S_TKc	26..312	CDD:214567	115/305 (38%)
cdk15	XP_005165792.1	STKc_PFTAIRE2	126..412	CDD:270852	115/306 (38%)
		PLN00009	127..415	CDD:177649	117/308 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0594
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900