Protein Alignment Cdk4 and cdk15

DIOPT Version :10

• Sequence 1: NP_477196.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: XP_031748614.1
• Gene: cdk15 / 780381
• XenbaseID: XB-GENE-961241
• Length: 435
• Species: Xenopus tropicalis
• Alignment Length: 351
• Identity: 129/351 - (36%)
• Similarity: 175/351 - (49%)
• Gaps: 64/351 - (18%)

  Fly     4 VRQLKRQKMS---QAKKFGD-------GDPF----NYQELNIIGEGAYGTVYRARDVITGNIVAL 54
            :|.|:.:..|   |.|..|.       |.||    :|..|..:|||:|.|||:....|.|.:|||
 Frog    67 IRSLRARSNSDPLQGKNLGQALQWQRRGLPFGNASSYLNLEKLGEGSYATVYKGISRINGQLVAL 131

  Fly    55 KKVRISLNENGVPMSTLREISLLKQLNASNHANIVKLYEVCQFLERDGQLLILLVFEHVEQDLSD 119
            |.:.:.. |.|||.:.:||.||||.|   .|||||.|:::.|..|     .:..|||:|..||:.
 Frog   132 KVISMKA-EEGVPFTAIREGSLLKGL---KHANIVLLHDIIQTRE-----TLTFVFEYVHTDLAQ 187

  Fly   120 LIDRLPKSGMSPPTIQRLSRELLTGVDFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLAK---- 180
            .:.:.| .|:.|..::....:||.|:.::|...|:||||||||||:|..|.||:||||||:
 Frog   188 YMSQHP-GGLLPYNVRLFMFQLLRGLAYIHHQHILHRDLKPQNLLISYIGELKLADFGLARAKSI 251

  Fly   181 ---TYGSEMKLTSVVVTLWYRAPEVLL-AQPYNSTVDIWSAACIIFEMFNRRALFPGTSE-KNQL 240
               ||.||      |||||||.|:||| |..|::.:|||.|.||..||......|.|.|: ..||
 Frog   252 PSQTYSSE------VVTLWYRPPDVLLGATDYSTDLDIWGAGCIFIEMLQGYPAFSGVSDIFEQL 310

  Fly   241 DRIFELTGRPTEQQWPQTISVALEHFPQRHPKRPKDFCPHLCKY---------------ADDLLN 290
            ::|:.:.|.|.|..||....:         |....::.. |.:|               |:||..
 Frog   311 EKIWSVIGTPAEDSWPGVSML---------PNYKTEWLT-LQEYQPFGNVWDGLGRSMGAEDLAE 365

  Fly   291 KMLSYDLHLRPSALACLEHDYFQQEP 316
            |||......|.||...|.|.:|...|
 Frog   366 KMLKGCPRERISAEDALLHKFFSTLP 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_477196.1	STKc_CDK4_6_like	26..312	CDD:270831	118/309 (38%)
cdk15	XP_031748614.1	Protein Kinases, catalytic domain	102..387	CDD:473864	118/310 (38%)