Protein Alignment Cdk4 and cdk14

DIOPT Version :9

• Sequence 1: NP_001286493.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: XP_021322413.1
• Gene: cdk14 / 572146
• ZFINID: ZDB-GENE-080220-44
• Length: 466
• Species: Danio rerio
• Alignment Length: 316
• Identity: 128/316 - (40%)
• Similarity: 181/316 - (57%)
• Gaps: 36/316 - (11%)

  Fly    17 KFGDGDPFNYQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLREISLLKQLN 81
            |||..|  :|::|..:|||:|.|||:.:..:.|.:||||.:|:. .|.|.|.:.:||.||||.|
Zfish   129 KFGKAD--SYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQ-EEEGTPFTAIREASLLKGL- 189

  Fly    82 ASNHANIVKLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSPPTIQRLSRELLTGVD 146
              .|||||.|:::....|     .:.||||:|..||...:|:.| .|:.|..::....:||.|:.
Zfish   190 --KHANIVLLHDIIHTKE-----TLTLVFEYVHTDLCQYMDKHP-GGLQPDNVRLFLFQLLRGLS 246

  Fly   147 FLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLAK-------TYGSEMKLTSVVVTLWYRAPEVLL 204
            ::|...|:||||||||||:|..|.||:||||||:       ||.:|      |||||||.|:|||
Zfish   247 YIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNE------VVTLWYRPPDVLL 305

  Fly   205 -AQPYNSTVDIWSAACIIFEMFNRRALFPGTSE-KNQLDRIFELTGRPTEQQWPQTISVALEHF- 266
             :..|::.:|:|...||..||....|.|||..: ::||:|||.:.|.|:|:.||...|  |.||
Zfish   306 GSTDYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPSEETWPGVHS--LPHFK 368

  Fly   267 PQR----HPKRPKDFCPHL--CKYADDLLNKMLSYDLHLRPSALACLEHDYFQQEP 316
            |.|    .||:.:.....|  ..:|::|.::.|......|.||.|.|.|:||...|
Zfish   369 PDRFTVYSPKKLRQAWNKLGYVDHAEELASRFLQCFPKKRLSAQAALHHEYFSHLP 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_001286493.1	STKc_CDK4_6_like	26..312	CDD:270831	121/301 (40%)
		S_TKc	26..312	CDD:214567	121/301 (40%)
cdk14	XP_021322413.1	STKc_PCTAIRE_like	135..420	CDD:270835	121/302 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0594
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900