Protein Alignment Cdk4 and cdk21

DIOPT Version :9

• Sequence 1: NP_001286493.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: XP_005164229.1
• Gene: cdk21 / 569515
• ZFINID: ZDB-GENE-131121-149
• Length: 305
• Species: Danio rerio
• Alignment Length: 290
• Identity: 124/290 - (42%)
• Similarity: 183/290 - (63%)
• Gaps: 6/290 - (2%)

  Fly    25 NYQELNIIGEGAYGTVYRARDV-ITGNIVALKKVRISLN-ENGVPMSTLREISLLKQLNASNHAN 87
            :|:.|..||:||||.||:||:. ....::|:|::.|... |:|:|...:||::||:::...||.|
Zfish    10 DYEILAEIGQGAYGKVYKAREKREQQRLIAVKRLNIPEEPESGIPQFMIREVALLRKIEHFNHPN 74

  Fly    88 IVKLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSPPTIQRLSRELLTGVDFLHSHR 152
            ||||..|....: :.:..:.||||:::|||:..:.|..:.|::...|:.:.|:||:|:||||::.
Zfish    75 IVKLMSVSAGWQ-NHKFDMTLVFEYIDQDLTTFLSRASEKGLAKDKIKDVMRQLLSGLDFLHTNS 138

  Fly   153 IIHRDLKPQNLLVSSQGHLKIADFGLAKTYGSEMKLTSVVVTLWYRAPEVLLAQPYNSTVDIWSA 217
            :|||||||.|:||||:|.:||||||||:.|...:.||..|||||||||||||...|.|:||:|||
Zfish   139 VIHRDLKPDNVLVSSRGEVKIADFGLARIYTYRIALTPCVVTLWYRAPEVLLQSSYMSSVDMWSA 203

  Fly   218 ACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWPQTISVALEHFPQRHPKRP-KDFCPHL 281
            .||..|:|..|.||.|.:|..||.:|||:.|.|.::.||....|.  :.|....|:| ......|
Zfish   204 GCIFAELFLLRPLFRGFTEIQQLQKIFEVIGLPGKEDWPVESPVC--YSPALVEKKPATQVLASL 266

  Fly   282 CKYADDLLNKMLSYDLHLRPSALACLEHDY 311
            ....:.||::.|:::...|.||...|.|.|
Zfish   267 TPEENGLLSQFLAFNPVHRISACEALAHPY 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_001286493.1	STKc_CDK4_6_like	26..312	CDD:270831	124/289 (43%)
		S_TKc	26..312	CDD:214567	124/289 (43%)
cdk21	XP_005164229.1	STKc_CDK4_6_like	11..297	CDD:270831	124/289 (43%)
		S_TKc	11..297	CDD:214567	124/289 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0594
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	285	1.000	Inparanoid score	I2832
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D419040at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm24416
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24056
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2222
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	7.930