Protein Alignment Cdk4 and cdk16

DIOPT Version :10

• Sequence 1: NP_477196.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: XP_021334043.1
• Gene: cdk16 / 559750
• ZFINID: ZDB-GENE-030131-2939
• Length: 537
• Species: Danio rerio
• Alignment Length: 321
• Identity: 123/321 - (38%)
• Similarity: 188/321 - (58%)
• Gaps: 34/321 - (10%)

  Fly     5 RQLKRQKMSQAKKFGDGDPFNYQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMS 69
            |:|:|..:|:   .|.|....|.:|:.:|||.|.|||:.|..:|.|:||||::|:. :|.|.|.:
Zfish   175 RRLRRVSLSE---IGFGKLETYVKLDKLGEGTYATVYKGRSKLTDNLVALKEIRLE-HEEGAPCT 235

  Fly    70 TLREISLLKQLNASNHANIVKLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSPPTI 134
            .:||:||||.|   .|||||.|:::..     .|..:.||||::::||...:|....| :....:
Zfish   236 AIREVSLLKDL---KHANIVTLHDIIH-----TQKSLTLVFEYLDKDLKQYLDDCGNS-IHMHNV 291

  Fly   135 QRLSRELLTGVDFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLA-------KTYGSEMKLTSVV 192
            :....:||.|:::.|..:::||||||||||::.:|.||:||||||       |||.:|      |
Zfish   292 KLFLFQLLRGLNYCHRRKVLHRDLKPQNLLINDRGELKLADFGLARAKSIPTKTYSNE------V 350

  Fly   193 VTLWYRAPEVLL-AQPYNSTVDIWSAACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWP 256
            ||||||.|::|| :..|::.:|:|...||.:||...|.||||::.:.:|..||:|.|.|||:.||
Zfish   351 VTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMSTGRPLFPGSTVEEELHFIFKLLGTPTEETWP 415

  Fly   257 QTISVALEHFPQRHPKRPKDFC-----PHLCKYADDLLNKMLSYDLHLRPSALACLEHDYF 312
             .|:...|.....:|:...| |     |.|.....:||:|:|.::...|.:|...:.|.||
Zfish   416 -GITSNEEFISYNYPRYRAD-CLHNHTPRLDNDGVELLSKLLQFEGKKRIAAEEAMRHPYF 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_477196.1	STKc_CDK4_6_like	26..312	CDD:270831	115/298 (39%)
cdk16	XP_021334043.1	STKc_PCTAIRE1	190..486	CDD:270854	117/303 (39%)