Protein Alignment Cdk4 and Cdk1

DIOPT Version :10

• Sequence 1: NP_477196.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_062169.1
• Gene: Cdk1 / 54237
• RGDID: 2319
• Length: 297
• Species: Rattus norvegicus
• Alignment Length: 296
• Identity: 129/296 - (43%)
• Similarity: 177/296 - (59%)
• Gaps: 19/296 - (6%)

  Fly    25 NYQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLREISLLKQLNASNHANIV 89
            :|.::..||||.||.||:.|...||.|||:||:|:...|.|||.:.:|||||||:|   .|.|||
  Rat     3 DYIKIEKIGEGTYGVVYKGRHRTTGQIVAMKKIRLESEEEGVPSTAIREISLLKEL---RHPNIV 64

  Fly    90 KLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSG-MSPPTIQRLSRELLTGVDFLHSHRI 153
            .|.:|   |.:|.:|  .|:||.:..||...:|.:|... |....::....::|.|:.|.||.|:
  Rat    65 SLQDV---LMQDSRL--YLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLYQILQGIVFCHSRRV 124

  Fly   154 IHRDLKPQNLLVSSQGHLKIADFGLAKTYGSEMKL-TSVVVTLWYRAPEVLLAQP-YNSTVDIWS 216
            :||||||||||:..:|.:|:||||||:.:|..::: |..|||||||:|||||... |::.|||||
  Rat   125 LHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWS 189

  Fly   217 AACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWPQTISVALEHFPQRHPK-RPKDFCPH 280
            ...|..|:..::.||.|.||.:||.|||...|.|..:.||:..|  |:.:....|| :|.....|
  Rat   190 IGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVES--LQDYKNTFPKWKPGSLASH 252

  Fly   281 LCKYAD----DLLNKMLSYDLHLRPSALACLEHDYF 312
            : |..|    |||:|||.||...|.|....|:|.||
  Rat   253 V-KNLDENGLDLLSKMLVYDPAKRISGKMALKHPYF 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_477196.1	STKc_CDK4_6_like	26..312	CDD:270831	127/293 (43%)
Cdk1	NP_062169.1	STKc_CDK1_euk	3..287	CDD:270845	127/294 (43%)