Protein Alignment Cdk4 and cdk9

DIOPT Version :10

• Sequence 1: NP_477196.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: XP_012823646.1
• Gene: cdk9 / 448039
• XenbaseID: XB-GENE-483721
• Length: 382
• Species: Xenopus tropicalis
• Alignment Length: 317
• Identity: 111/317 - (35%)
• Similarity: 172/317 - (54%)
• Gaps: 30/317 - (9%)

  Fly    26 YQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLREISLLKQLNASNHANIVK 90
            |:.|..||:|.:|.|::|:...||..||||||.:...:.|.|::.||||.:|:.|   .|.|:|.
 Frog    19 YERLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLL---KHENVVN 80

  Fly    91 LYEVCQFLERDGQLL-------------ILLVFEHVEQDLSDLIDRL-PKSGMSPPTIQRLSREL 141
            |.|:|:.......|:             |.|||:..|.||:.|:... .|..:|  .|:::.:.|
 Frog    81 LIEICRTKNSLAHLVSPTANQYNRCKGTIFLVFDFCEHDLAGLLSNAHVKFTLS--EIKKVMQML 143

  Fly   142 LTGVDFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLAKTY-----GSEMKLTSVVVTLWYRAPE 201
            |.|:.::|.::|:|||:|..|:|::..|.||:||||||:.:     ....|.|:.|||||||.||
 Frog   144 LNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNKYTNRVVTLWYRPPE 208

  Fly   202 VLLAQ-PYNSTVDIWSAACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWPQTISVALE- 264
            :||.: .|...:|:|.|.||:.||:.|..:..|.:|::||..|.:|.|..|.:.||......|.
 Frog   209 LLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLTLISQLCGSITPEVWPNVDKYELYQ 273

  Fly   265 --HFPQRHPKRPKDFCPHLCK--YADDLLNKMLSYDLHLRPSALACLEHDYFQQEPL 317
              ..|:...::.|:......|  ||.||::|:|..|...|..:...|.||:|..:|:
 Frog   274 KLELPKGQKRKVKERLKAYVKDLYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPM 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_477196.1	STKc_CDK4_6_like	26..312	CDD:270831	109/310 (35%)
cdk9	XP_012823646.1	STKc_CDK9	6..325	CDD:270848	109/310 (35%)