Protein Alignment Cdk4 and Cdk2

DIOPT Version :9

• Sequence 1: NP_001286493.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_001163666.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Alignment Length: 296
• Identity: 133/296 - (44%)
• Similarity: 174/296 - (58%)
• Gaps: 21/296 - (7%)

  Fly    25 NYQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLREISLLKQLNASNHANIV 89
            |:|....||||.||.||:||...||..|||||:|:.....|||.:.:|||||||.|   .|.|:|
  Fly     7 NFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNL---KHPNVV 68

  Fly    90 KLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSPPTIQRLSRELLTGVDFLHSHRII 154
            :|::|.    ..|..| .::||::..||..|:|: .|...:|..|:....::|..|.|.|::||:
  Fly    69 QLFDVV----ISGNNL-YMIFEYLNMDLKKLMDK-KKDVFTPQLIKSYMHQILDAVGFCHTNRIL 127

  Fly   155 HRDLKPQNLLVSSQGHLKIADFGLAKTYGSEMK-LTSVVVTLWYRAPEVLLAQPYNST-VDIWSA 217
            |||||||||||.:.|.:|:||||||:.:...|: .|..||||||||||:||...:.|| |||||.
  Fly   128 HRDLKPQNLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSL 192

  Fly   218 ACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWPQTISVALEHFPQRHPK-----RPKDF 277
            .||..||..||:||||.||.:||.|||.....|.|..||..  ..|..|..:.|:     .|:..
  Fly   193 GCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGV--TQLPDFKTKFPRWEGTNMPQPI 255

  Fly   278 CPHLCKYADDLLNKMLSYDLHLRPSALACLEHDYFQ 313
            ..|   .|.:|:..||.||.:||.||...|:|.||:
  Fly   256 TEH---EAHELIMSMLCYDPNLRISAKDALQHAYFR 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_001286493.1	STKc_CDK4_6_like	26..312	CDD:270831	130/292 (45%)
		S_TKc	26..312	CDD:214567	130/292 (45%)
Cdk2	NP_001163666.1	PLN00009	5..293	CDD:177649	133/296 (45%)
		STKc_CDK1_CdkB_like	8..287	CDD:270829	130/292 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442452
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0594
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24056
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840