Protein Alignment Cdk4 and Pitslre

DIOPT Version :9

• Sequence 1: NP_001286493.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_649251.2
• Gene: Pitslre / 40292
• FlyBaseID: FBgn0016696
• Length: 952
• Species: Drosophila melanogaster
• Alignment Length: 317
• Identity: 125/317 - (39%)
• Similarity: 178/317 - (56%)
• Gaps: 43/317 - (13%)

  Fly    26 YQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLREI-SLLKQLNASNHANIV 89
            :|.||.|.||.||.||||:|..|..|||||::::...:.|.|:::|||| :|||    ..|.|||
  Fly   558 FQCLNRIEEGTYGVVYRAKDKRTNEIVALKRLKMEKEKEGFPITSLREINTLLK----GQHPNIV 618

  Fly    90 KLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLP--KSGMSPPTIQRLSRELLTGVDFLHSHR 152
            .:.|:......|   .|.:|.::||.||..|::.:.  |....|..::.|:::||..|..||.:.
  Fly   619 TVREIVVGSNMD---KIFIVMDYVEHDLKSLMETMKNRKQSFFPGEVKCLTQQLLRAVAHLHDNW 680

  Fly   153 IIHRDLKPQNLLVSSQGHLKIADFGLAKTYGSEM-KLTSVVVTLWYRAPEVLLAQP-YNSTVDIW 215
            |:|||||..|||:|.:|.||:.|||||:.|||.: |.||:||||||||||:||..| |::.:|:|
  Fly   681 ILHRDLKTSNLLLSHKGILKVGDFGLAREYGSPIKKYTSLVVTLWYRAPELLLCSPVYSTPIDVW 745

  Fly   216 SAACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWP--------------------QTIS 260
            |..||..|......||||.||.::|:|||:..|.|.|:.||                    ..:|
  Fly   746 SVGCIFAEFLQMLPLFPGKSEIDELNRIFKELGTPNEKIWPGYTELPAVKNMLSQNSQFTEYPVS 810

  Fly   261 VALEHFPQRHPKRPKDFCPHLCKYADDLLNKMLSYDLHLRPSALACLEHDYFQQEPL 317
            ...:||.::           ..:....||..:|:||...|.||.|.|:|.:|::.||
  Fly   811 QLRKHFQEK-----------TSEMGLSLLQGLLTYDPKQRLSADAALKHGFFKELPL 856

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_001286493.1	STKc_CDK4_6_like	26..312	CDD:270831	122/310 (39%)
		S_TKc	26..312	CDD:214567	122/310 (39%)
Pitslre	NP_649251.2	STKc_CDC2L1	552..851	CDD:173741	122/310 (39%)
		PLN00009	555..854	CDD:177649	123/313 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442400
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24056
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940