DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cdk4 and cdk1

DIOPT Version :9

Sequence 1:NP_001286493.1 Gene:Cdk4 / 36854 FlyBaseID:FBgn0016131 Length:317 Species:Drosophila melanogaster
Sequence 2:NP_988908.1 Gene:cdk1 / 394503 XenbaseID:XB-GENE-482750 Length:302 Species:Xenopus tropicalis


Alignment Length:295 Identity:130/295 - (44%)
Similarity:175/295 - (59%) Gaps:19/295 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly    26 YQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLREISLLKQLNASNHANIVK 90
            |.::..||||.||.||:.|...||.:||:||:|:...|.|||.:.:|||||||:|   .|.|||.
 Frog     4 YTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKEL---QHPNIVC 65

  Fly    91 LYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSPPT--IQRLSRELLTGVDFLHSHRI 153
            |.:|   |.:|.:|  .|:||.:..||...:|.:| ||....|  ::....::|.|:.|.||.|:
 Frog    66 LLDV---LMQDSRL--YLIFEFLSMDLKKYLDSIP-SGQYIDTMLVKSYLYQILQGIVFCHSRRV 124

  Fly   154 IHRDLKPQNLLVSSQGHLKIADFGLAKTYGSEMKL-TSVVVTLWYRAPEVLLAQ-PYNSTVDIWS 216
            :||||||||||:.|:|.:|:||||||:.:|..::: |..|||||||||||||.. .|::.||:||
 Frog   125 LHRDLKPQNLLIDSKGVIKLADFGLARAFGIPVRVYTHEVVTLWYRAPEVLLGSVRYSTPVDVWS 189

  Fly   217 AACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWPQTISVALEHFPQRHPKRPKDFCPHL 281
            ...|..|:..::.||.|.||.:||.|||...|.|..:.||:..|  |:.:....||.........
 Frog   190 IGTIFAEIATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVES--LQDYKNTFPKWKGGNLSAN 252

  Fly   282 CKYAD----DLLNKMLSYDLHLRPSALACLEHDYF 312
            .|..|    |||:|||.||...|.||...|.|.||
 Frog   253 VKNIDKDGLDLLSKMLIYDPAKRISARKALLHPYF 287

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cdk4NP_001286493.1 STKc_CDK4_6_like 26..312 CDD:270831 128/293 (44%)
S_TKc 26..312 CDD:214567 128/293 (44%)
cdk1NP_988908.1 STKc_CDK1_euk 3..287 CDD:270845 128/293 (44%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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