Protein Alignment Cdk4 and cdk1

DIOPT Version :10

• Sequence 1: NP_477196.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_988908.1
• Gene: cdk1 / 394503
• XenbaseID: XB-GENE-482750
• Length: 302
• Species: Xenopus tropicalis
• Alignment Length: 295
• Identity: 130/295 - (44%)
• Similarity: 175/295 - (59%)
• Gaps: 19/295 - (6%)

  Fly    26 YQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLREISLLKQLNASNHANIVK 90
            |.::..||||.||.||:.|...||.:||:||:|:...|.|||.:.:|||||||:|   .|.|||.
 Frog     4 YTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKEL---QHPNIVC 65

  Fly    91 LYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSPPT--IQRLSRELLTGVDFLHSHRI 153
            |.:|   |.:|.:|  .|:||.:..||...:|.:| ||....|  ::....::|.|:.|.||.|:
 Frog    66 LLDV---LMQDSRL--YLIFEFLSMDLKKYLDSIP-SGQYIDTMLVKSYLYQILQGIVFCHSRRV 124

  Fly   154 IHRDLKPQNLLVSSQGHLKIADFGLAKTYGSEMKL-TSVVVTLWYRAPEVLLAQ-PYNSTVDIWS 216
            :||||||||||:.|:|.:|:||||||:.:|..::: |..|||||||||||||.. .|::.||:||
 Frog   125 LHRDLKPQNLLIDSKGVIKLADFGLARAFGIPVRVYTHEVVTLWYRAPEVLLGSVRYSTPVDVWS 189

  Fly   217 AACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWPQTISVALEHFPQRHPKRPKDFCPHL 281
            ...|..|:..::.||.|.||.:||.|||...|.|..:.||:..|  |:.:....||.........
 Frog   190 IGTIFAEIATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVES--LQDYKNTFPKWKGGNLSAN 252

  Fly   282 CKYAD----DLLNKMLSYDLHLRPSALACLEHDYF 312
            .|..|    |||:|||.||...|.||...|.|.||
 Frog   253 VKNIDKDGLDLLSKMLIYDPAKRISARKALLHPYF 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_477196.1	STKc_CDK4_6_like	26..312	CDD:270831	128/293 (44%)
cdk1	NP_988908.1	STKc_CDK1_euk	3..287	CDD:270845	128/293 (44%)