Protein Alignment Cdk4 and Eip63E

DIOPT Version :10

• Sequence 1: NP_477196.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_001261373.1
• Gene: Eip63E / 38433
• FlyBaseID: FBgn0005640
• Length: 538
• Species: Drosophila melanogaster
• Alignment Length: 337
• Identity: 125/337 - (37%)
• Similarity: 177/337 - (52%)
• Gaps: 48/337 - (14%)

  Fly     7 LKRQKMSQAKK----FGDGDPFNYQE----LNIIGEGAYGTVYRARDVITGNIVALKKVRISLNE 63
            |.:|:....:|    ||...||..||    |..:|||:|.|||:....:|...||||::|:. .|
  Fly   178 LNKQETHPRRKRFSAFGGDSPFGKQEAYVKLEPLGEGSYATVYKGFSKLTYQRVALKEIRLQ-EE 241

  Fly    64 NGVPMSTLREISLLKQLNASNHANIVKLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSG 128
            .|.|.:.:||.||||:|   .|:|||.|:::....|     .:..|||:|..|||..:::.| .|
  Fly   242 EGAPFTAIREASLLKEL---KHSNIVTLHDIVHTRE-----TLTFVFEYVNTDLSQYMEKHP-GG 297

  Fly   129 MSPPTIQRLSRELLTGVDFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLAK-------TYGSEM 186
            :....::....:||.|:.:.|..|::|||:||||||:|..|.||:||||||:       ||..|
  Fly   298 LDHRNVRLFLFQLLRGLSYCHKRRVLHRDVKPQNLLISDCGELKLADFGLARAKSVPSHTYSHE- 361

  Fly   187 KLTSVVVTLWYRAPEVLL-AQPYNSTVDIWSAACIIFEMFNRRALFPGTSEK-NQLDRIFELTGR 249
                 |||||||.|:||| :..|::::|:|...||..||......|||..:. :|||:||:|.|.
  Fly   362 -----VVTLWYRPPDVLLGSTEYSTSLDMWGVGCIFVEMVTGMPTFPGIRDTYDQLDKIFKLLGT 421

  Fly   250 PTEQQWPQTISVALEHFPQRHPK-----RPKDFCPHLCKYAD-----DLLNKMLSYDLHLRPSAL 304
            |||..||     .:.|||...|.     ||:....:..:..|     .:.|..|..:...|..|.
  Fly   422 PTEDTWP-----GVTHFPGYKPHKLGFYRPRKLGHNFPRLYDIIEGETIANGFLQLNPEQRLGAD 481

  Fly   305 ACLEHDYFQQEP 316
            ..|:|.||.|.|
  Fly   482 DALQHPYFAQLP 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_477196.1	STKc_CDK4_6_like	26..312	CDD:270831	114/308 (37%)
Eip63E	NP_001261373.1	STKc_PCTAIRE_like	204..489	CDD:270835	112/305 (37%)