Protein Alignment Cdk4 and Cdkl4

DIOPT Version :10

• Sequence 1: NP_477196.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_001028615.1
• Gene: Cdkl4 / 381113
• MGIID: 3587025
• Length: 342
• Species: Mus musculus
• Alignment Length: 296
• Identity: 101/296 - (34%)
• Similarity: 160/296 - (54%)
• Gaps: 44/296 - (14%)

  Fly    26 YQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLREISLLKQLNASNHANIVK 90
            |::|..||||:||.|::.|:..:|.:||:||...|.::..|....||||.:||||   .|.|:|.
Mouse     4 YEKLAKIGEGSYGVVFKCRNKSSGQVVAIKKFVESEDDRVVRKIALREIRMLKQL---KHPNLVN 65

  Fly    91 LYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSPPTIQRLSRELLTGVDFLHSHRIIH 155
            |.||.:...:     :.||||:.:..|.:.::|.| :|:|...|:.:..:.|..::|.|.|..||
Mouse    66 LIEVFRRKRK-----MHLVFEYCDHTLLNELERNP-NGVSDGVIKSVLWQTLQALNFCHKHNCIH 124

  Fly   156 RDLKPQNLLVSSQGHLKIADFGLAKTYGSEMKLTSVVVTLWYRAPEVLLAQ-PYNSTVDIWSAAC 219
            ||:||:|:|::.||.:||.|||.|:........|..|.|.||||||:|:.. .|.|:||:|:..|
Mouse   125 RDVKPENILITKQGMIKICDFGFARILIPGDAYTDYVATRWYRAPELLVGDTKYGSSVDVWAVGC 189

  Fly   220 IIFEMFNRRALFPGTSEKNQLDRIFELTGR--PTEQ------QWPQTISVALEHFPQRHPKRPKD 276
            :..|:...:.|:||.|:.:||..|....|:  |..|      |:.:.||:     |:     |:|
Mouse   190 VFAELLTGQPLWPGKSDVDQLYLIIRTLGKLIPRHQSIFRSNQFFRGISI-----PE-----PED 244

  Fly   277 FCPHLCKYADDLLNKMLSYDLHLRPSALA----CLE 308
            .         :.|.:..|   :::|.||:    ||:
Mouse   245 M---------ETLEEKFS---NVQPVALSFMKGCLK 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_477196.1	STKc_CDK4_6_like	26..312	CDD:270831	101/296 (34%)
Cdkl4	NP_001028615.1	STKc_CDKL1_4	2..286	CDD:270837	101/296 (34%)
		[NKR]KIAxRE	45..51		1/5 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	295..328