Protein Alignment Cdk4 and Cdk9

DIOPT Version :9

• Sequence 1: NP_001286493.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_477226.2
• Gene: Cdk9 / 37586
• FlyBaseID: FBgn0019949
• Length: 404
• Species: Drosophila melanogaster
• Alignment Length: 331
• Identity: 117/331 - (35%)
• Similarity: 185/331 - (55%)
• Gaps: 28/331 - (8%)

  Fly     7 LKRQKMSQAKKFGDGDPFN-YQELNIIGEGAYGTVYRARDVITGN--IVALKKVRISLNENGVPM 68
            :::||..:...|...|..| |:::..||:|.:|.|::||:. .||  .||:|||.:...:.|.|:
  Fly    30 MEKQKYIEDYDFPYCDESNKYEKVAKIGQGTFGEVFKAREK-KGNKKFVAMKKVLMDNEKEGFPI 93

  Fly    69 STLREISLLKQLNASNHANIVKLYEVC--QFLERDG-QLLILLVFEHVEQDLSDLIDRLPKSGMS 130
            :.||||.:|:.|   .|.|:|.|.|:|  :....:| :....|||:..|.||:.|:..: ....|
  Fly    94 TALREIRILQLL---KHENVVNLIEICRTKATATNGYRSTFYLVFDFCEHDLAGLLSNM-NVKFS 154

  Fly   131 PPTIQRLSRELLTGVDFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLAKTYG-----SEMKLTS 190
            ...|:::.::||.|:.::||::|:|||:|..|:|::..|.||:||||||:.:.     |:.:.|:
  Fly   155 LGEIKKVMQQLLNGLYYIHSNKILHRDMKAANVLITKHGILKLADFGLARAFSIPKNESKNRYTN 219

  Fly   191 VVVTLWYRAPEVLLA-QPYNSTVDIWSAACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQ 254
            .|||||||.||:||. :.|...||:|.|.||:.||:.|..:..|.:|:.||..|.:|.|..|...
  Fly   220 RVVTLWYRPPELLLGDRNYGPPVDMWGAGCIMAEMWTRSPIMQGNTEQQQLTFISQLCGSFTPDV 284

  Fly   255 WPQTISVALE---HFPQRHPKRPKDFCPHLCKYAD-----DLLNKMLSYDLHLRPSALACLEHDY 311
            ||....:.|.   ..|:...:|.|:   .|..|..     |||:|:|:.|...|..|...|.||:
  Fly   285 WPGVEELELYKSIELPKNQKRRVKE---RLRPYVKDQTGCDLLDKLLTLDPKKRIDADTALNHDF 346

  Fly   312 FQQEPL 317
            |..:|:
  Fly   347 FWTDPM 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk4	NP_001286493.1	STKc_CDK4_6_like	26..312	CDD:270831	110/304 (36%)
		S_TKc	26..312	CDD:214567	110/304 (36%)
Cdk9	NP_477226.2	STKc_CDK9	37..347	CDD:270848	113/317 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442445
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24056
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030